You Searched For: Rolipram

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R-(-)-Rolipram ≥98% (by HPLC)

Catalog Number: (ENZOBMLPD1770005)

Supplier: ENZO LIFE SCIENCES AG

Description: R-enantiomer of rolipram which is more active at inhibition of PDE IV, Ki=06 µM. 10-fold more active than S-rolipram at inhibition of PDE IV. Inhibits antigen-induced contraction of guinea-pig colonic smooth muscle, EC50=0.1 µM.

UOM: 1 * 5 mg

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Rolipram ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES AG

Description: PDE inhibitor

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Rolipram ≥99%

Supplier: Apollo Scientific

Description: Rolipram has two enantiomeric forms, R(-) and S(+). This product is the racemic mixture of the two enantiomers.

Anti-PDE8A Rabbit Polyclonal Antibody

Catalog Number: (PRSI48-315)

Supplier: ProSci Inc.

Description: Phosphodiesterase 8A, a high affinity, cAMP-specific phosphodiesterase, has been implicated in penile erectile dysfunction. PDE8A activity is inhibited by dipyridamole, but not by rolipram, zaprinast, or IBMX. At least five splice variants and four protein isoforms have been reported.

UOM: 1 * 50 µG

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Anti-PDE8B Rabbit Polyclonal Antibody

Catalog Number: (PRSI48-317)

Supplier: ProSci Inc.

Description: Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.

UOM: 1 * 50 µG

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Anti-PDE9A Rabbit Polyclonal Antibody

Catalog Number: (PRSI48-318)

Supplier: ProSci Inc.

Description: Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.

UOM: 1 * 50 µG

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