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Anti-BEST2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11041R-CY5)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl
Image Unavailable-AGLS200415

Deoxynucleotide mix

Catalog Number: (AGLS200415)
Supplier: AGILENT
Description: The PCR grade deoxynucleotide mix includes 25 mM of each standard dNTP (GATC) for use with any PCR application, including real-time quantitative PCR.
UOM: 1 * 1 items
Product Image-733-1313

VWR®, Taq DNA polymerase

Supplier: VWR Chemicals
Description: VWR® Taq DNA Polymerase is an ultra-pure, thermostable, recombinant DNA polymerase, which provides robust PCR performance in a wide range of PCR applications, without time-consuming optimisation. The enzyme is isolated from <i>Thermus aquaticus</i>, and has a molecular weight of approximately 94 kDa. VWR® <i>Taq</i> DNA Polymerase has both a 5' to 3' DNA polymerase and a double strand 5' to 3' exonuclease activity. It leaves an A overhang, which makes the enzyme ideal for TA cloning.

MSDS Certificates

Product Image-SOLUN-9515-10

TriLink® CleanAmp® 7-Deaza-dGTP

Supplier: TriLink BioTechnologies
Description: CleanAmp® dNTPs are chemically-modified nucleotides designed to improve specificity, sensitivity, and robustness of your PCR.

New Product

Product Image-SOLUN-2069-5

TriLink® 7-Deaza-7-Propargylamino-2'-deoxyguanosine-5'-Triphosphate

Supplier: TriLink BioTechnologies
Description: TriLink® 7-Deaza-7-Propargylamino-2'-deoxyguanosine-5'-Triphosphate

New Product

Image Unavailable-BTRABR1400901

Cell-free protein synthesis, rapid translation system (RTS) vectors

Supplier: biotechrabbit
Description: Expression vectors for PCR-based generation of linear templates.

Image Unavailable-BOSSBS-11041R-CY3

Anti-BEST2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11041R-CY3)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11041R-A488

Anti-BEST2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-11041R-A488)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl
Product Image-SOLUN-1112-5

TriLink® 2'-O-Methyl-N6-Methyladenosine-5'-Triphosphate

Supplier: TriLink BioTechnologies
Description: TriLink® 2'-O-Methyl-N6-Methyladenosine-5'-Triphosphate

New Product

Image Unavailable-BOSSBS-11041R-A750

Anti-Bestrophin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-11041R-A750)
Supplier: Bioss
Description: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterised channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
UOM: 1 * 100 µl
Product Image-BTRABR1402401

Cell-free protein synthesis, rapid translation system (RTS) linear template kits

Supplier: biotechrabbit
Description: Expression kits for PCR-based generation of linear templates.

Product Image-SOLUN-9506-2

TriLink® CleanAmp® dNTP Mix

Supplier: TriLink BioTechnologies
Description: CleanAmp® dNTPs are chemically-modified nucleotides designed to improve specificity, sensitivity, and robustness of your PCR.

New Product

Product Image-SOLUN-9504-2

TriLink® CleanAmp® 7-deaza-dGTP Mix

Supplier: TriLink BioTechnologies
Description: CleanAmp® dNTPs are chemically-modified nucleotides designed to improve specificity, sensitivity, and robustness of your PCR.

New Product

Product Image-733-2406

VWR®, Taq DNA polymerase glycerol free

Supplier: VWR Chemicals
Description: VWR® Taq DNA Polymerase Glycerol Free 5U/µl is a thermostable recombinant DNA polymerase, which exhibits very high activity in primer extension and other molecular biology applications. The enzyme is isolated from Thermus aquaticus and has a molecular weight of approximately 94 kDa.

MSDS

Image Unavailable-AGLS240207

PCR cloning kits, StrataClone

Supplier: AGILENT
Description: The StrataClone PCR cloning kit allows high-efficiency, 5-minute cloning of PCR products at room temperature, using the efficient DNA rejoining activity of DNA topoisomerase I and the DNA recombination activity of Cre recombinase.

Product Image-SOLUN-8008-5

TriLink® Uridine-5'-O-(1-Thiotriphosphate)

Supplier: TriLink BioTechnologies
Description: TriLink® Uridine-5'-O-(1-Thiotriphosphate)

New Product

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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