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Catalog Number: (BOSSBS-5958R-CY3)
Supplier: Bioss
Description: Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells. The expression of MLL-AF-4 influences the production of protein cyclin-dependent kinase inhibitor (CDKN1B), suggesting that inhibition of MLL-AF-4 expression may be a powerful and highly specific treatment of chemotherapy-resistant leukemia.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5958R-A750)
Supplier: Bioss
Description: Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells. The expression of MLL-AF-4 influences the production of protein cyclin-dependent kinase inhibitor (CDKN1B), suggesting that inhibition of MLL-AF-4 expression may be a powerful and highly specific treatment of chemotherapy-resistant leukemia.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5958R-FITC)
Supplier: Bioss
Description: Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells. The expression of MLL-AF-4 influences the production of protein cyclin-dependent kinase inhibitor (CDKN1B), suggesting that inhibition of MLL-AF-4 expression may be a powerful and highly specific treatment of chemotherapy-resistant leukemia.
UOM: 1 * 100 µl


Catalog Number: (630-3267)
Supplier: VWR Collection
Description: Routine inverted fluorescence microscopes for transmitted brightfield, darkfield, phase contrast and fluorescence observations. Ideal for tissue culture research in clinical and biotechnology laboratories.
UOM: 1 * 1 items


Catalog Number: (612-7179)
Supplier: VWR Collection
Description: The VWR® pipette controller is a compact and portable device that features multiple user-selectable modes and speeds to perform a wide range of liquid handling applications. Each device is supplied with a 3-year warranty.
UOM: 1 * 1 items


Catalog Number: (444-0928)
Supplier: GRANT INSTRUMENTS
Description: Powerful and efficient microprocessor-controlled, multifunctional orbital shaker with rotation, reciprocation and vibration. The shaker has a reliable direct drive system, accommodates loads up to 8 kg, and enables mixing optimisation whether in flasks, beakers, Petri dishes or other laboratory vessels. The PSU-20i is easy to operate, with simple set-up of multi-segment programs via push buttons and the 2-line LCD status display.
UOM: 1 * 1 items


Supplier: Plum Safety
Description: Belt bag for 200 ml eyewash bottles, For: Plum, Eyewash station

Supplier: VWR Collection
Description: Advanced routine fluorescence microscope for transmitted brightfield and fluorescence observations with high quality IOS W-Plan or IOS W-Plan F (Semi-Apo) objectives. Suitable for educational and laboratory applications.

Catalog Number: (HEID14-007-005-45)
Supplier: Heidolph Instruments GmbH & Co.KG
Description: Power cord UK
UOM: 1 * 1 items


Supplier: DWK Life Sciences
Description: Stand for battery powered crimping tool

Catalog Number: (SENA0096647494838)
Supplier: SenseAnywhere
Description: This smart probe interface featuring a digital SenseAnywhere Bus interface has been especially designed to connect an existing 4-wire Pt100 Probe to the SenseAnywhere Monitoring System.
UOM: 1 * 1 items


Catalog Number: (GEAG05.25086EU)
Supplier: Gerber Instruments AG
Description: Power cable, EU-plug
UOM: 1 * 1 items


Supplier: LABCONCO
Description: Utility shelves attachs to the rear baffle perforations, has a scalloped front edge to support scalpels, forceps and other supplies, 2,3 kg

Supplier: 3M
Description: Speedglas™ Outside protection plates are designed for use with 3M™ Speedglas™ welding helmets and filters to protect the welding filter from sparks and spatter.

Supplier: 3M
Description: TR-640, battery charger cradle, replacement part for the TR-641 and TR-644 battery charger kits, Versaflo™

Catalog Number: (111-2225)
Supplier: 3M
Description: 3M™ Versaflo™ V-Series supplied air regulators offer protection against dust, mist, fumes, gases or vapours and combination hazards e.g. paint spray. Supplied air regulators do not offer protection in confined spaces, oxygen deficient atmospheres or for asbestos stripping. The 3M™ Versaflo™ V-500E supplied air regulator is a balanced, belt-worn, easy to adjust regulator specifically designed to ensure smooth airflow, safety and comfort.
UOM: 1 * 1 items


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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