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Malonyl coenzyme A lithium salt ≥90%

Supplier: Cayman Chemical
Description: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Image Unavailable-07441-10MG

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Supplier: Merck
Description: Organic Standard, Malonyl-ʟ-carnitine lithium salt

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Cerulenin ≥98%, crystalline solid

Supplier: Cayman Chemical
Description: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-12952R-A680)
Supplier: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-12954R-A680)
Supplier: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (BOSSBS-12954R-A750)
Supplier: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12952R-A750)
Supplier: Bioss
Description: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-APOSBIC7401-100MG

Coenzyme A trilithium salt

Supplier: Apollo Scientific
Description: Coenzyme A trilithium salt

Certificates

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4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Supplier: Cayman Chemical
Description: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

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Coenzyme A sodium salt hydrate ≥95%

Supplier: Cayman Chemical
Description: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

Image Unavailable-APOSBIA1091-100MG

Acetyl-Coenzyme A Trilithium Salt

Supplier: Apollo Scientific
Description: Acetyl-Coenzyme A Trilithium Salt

Image Unavailable-8.22084.0100

L(+)-Lithium lactate for synthesis, Sigma-Aldrich®

Supplier: Merck
Description: L(+)-Lithium lactate for synthesis, Sigma-Aldrich®

MSDS

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Riboflavin 5'-monophosphate sodium salt hydrate

Supplier: Cayman Chemical
Description: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

Image Unavailable-ENZOALX460003G010

Calcium pantothenate ≥98% (by HPLC)

Catalog Number: (ENZOALX460003G010)
Supplier: ENZO LIFE SCIENCES AG
Description: Precursor for coenzyme A biosynthesis.
UOM: 1 * 10 g

New Product


Image Unavailable-19533-5MG

Supelco® Organic Reference Standard, Geranyl Pyrophosphate Lithium Salt

Catalog Number: (19533-5MG)
Supplier: Merck
Description: Organic Standard, Geranyl pyrophosphate lithium salt
UOM: 1 * 5 mg
Product Image-0782-100G

Lithium dodecyl sulphate ≥99%, high purity

Supplier: VWR Chemicals
Description: Lithium dodecyl sulphate ≥99%, high purity

MSDS

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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