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Catalog Number: (MILFXF5423050)
Supplier: Merck
Description: Millivac™ Mini vacuum pumps are compact, maintenance-free pumps that provide a consistent source of vacuum for filtration and other laborabory applications. A patented diaphragm design has reduced the footprint of the pumps compared to conventional models.
UOM: 1 * 1 items


Supplier: EBRO
Description: <p>The EBI 12-T220 is a precise temperature data logger for process validation in laboratories and the pharmaceutical industry. With a temperature range of –200 to +200 °C and an accuracy of up to 0,05 °C, it enables precise temperature measurements in critical applications such as sterilisation and disinfection.</p>

Supplier: Merck
Description: In addition to spare cuvettes and light sources, the pour and flow cells have been developed to improve efficiency. The pour through assembly provides a single one-time cuvette alignment and simplified rinsing.
Catalog Number: (BOSSBS-0526R-CY5)
Supplier: Bioss
Description: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-3252R-CY3)
Supplier: Bioss
Description: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
UOM: 1 * 100 µl


Supplier: Avantor
Description: Avantor excipients are used during the formulation process in a wide range of applications. Avantor provides high-purity and performance excipients that serve as fillers, binders, disintegrants, lubicants, flavors, emulsifiers and preservatives.
Catalog Number: (BOSSBS-11219R-CY5)
Supplier: Bioss
Description: Exportin 5 (XPO5) is a member of the importin β family of proteins and functions in tRNA export in a sequence dependent fashion. More recently, it has been shown to export pre-miRNA by a RanGTPase-driven process from the nucleus to the cytoplasm, where pre-miRNA processing occurs to produce mature miRNAs. Study of the miRNA biosynthesis pathway is essential in understanding the process of oncogenesis as global downregulation of miRNAs and the resulting alterations in the expression of tumor suppressor and oncogenic proteins is a common phenotype of cancers cells . Research studies have shown disruption of exportin 5 functions in many types of cancers including breast and lung, where pre-miRNA accumulates in the nucleus and miRNA maturation is impaired.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-5731R-A350)
Supplier: Bioss
Description: Mad2L1 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore spindle attachment and delays the onset of anaphase when this process is not complete. It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
UOM: 1 * 100 µl


Supplier: Brady
Description: Super chemical-resistant polyester (B-481) is designed for use in the slide staining process and other laboratory ID which requires superior chemical resistance.

Catalog Number: (BOSSBS-9480R)
Supplier: Bioss
Description: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.
UOM: 1 * 100 µl


Catalog Number: (92688-100MG)
Supplier: Merck
Description: 5,5-Dimethyl-1-pyrroline N-oxide is a reagent generally used either as a free-radical spin-trapping agent, or electrophilic component during the synthesis of pyrrolidine derivatives. It may also be considered as 1,3-dipole in cycloaddition processes.
UOM: 1 * 100 mg


Catalog Number: (BOSSBS-12242R-A647)
Supplier: Bioss
Description: Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11532R-CY5)
Supplier: Bioss
Description: Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13591R-A750)
Supplier: Bioss
Description: Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalysed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.
UOM: 1 * 100 µl


Supplier: VWR Seradigm
Description: Avantor Seradigm Select Grade FBS provides superior performance and consistency in cost-sensitive applications.

Catalog Number: (BOSSBS-13591R-HRP)
Supplier: Bioss
Description: Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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