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Image Unavailable-BOSSBS-0754R-A555

Anti-PCNA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-0754R-A555)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0754R-CY5

Anti-PCNA Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-0754R-CY5)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2006R-CY5

Anti-PCNA-proliferation Marker Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-2006R-CY5)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Product Image-LBCP780701050

Small tray dryer, FreeZone®

Catalog Number: (LBCP780701050)
Supplier: LABCONCO
Description: These FreeZone® small tray dryers provide precise control and program flexibility for consistent performance and are designed for lyophilising small to moderate bulk sample loads or numerous sample batches.
UOM: 1 * 1 items

Environmentally Preferable


Product Image-1.99006.0001

Buffer solutions in sachets, Certipur®, Supelco®

Supplier: Merck
Description: For calibration of pH meters.

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Product Image-HICH87703

Avantor® Alltima HP, HPLC Columns, C18-EPS, 3 µm

Supplier: Avantor
Description: Avantor® Alltima HP columns combine a range of different phase chemistries with high purity silica. Avantor® Alltima HP columns contain the highest carbon load for superior retention and loadability.

Product Image-MMMPBPPFV9BFD

Mini flip-top vial with 9 ml Butterfield's buffer

Catalog Number: (MMMPBPPFV9BFD)
Supplier: 3M Food Safety
Description: The 3M™ Mini Flip-Top Vial with 9 ml Butterfield's Buffer is a leak-resistant plastic cylinder with a flip-open lid that seals securely for safe shipping and handling.
UOM: 1 * 100 items
Image Unavailable-41006.

Buffer, TBE solution 5X concentrate (TRIS-borate-EDTA buffer)

Catalog Number: (41006.)
Supplier: Biotium
Description: Running Buffer, TBE buffer solution 5X concentrate (TRIS-borate-EDTA buffer)
UOM: 1 * 4 L
Product Image-ROCKMB-007

Buffers, TE solutions 10X concentrates (TRIS-EDTA buffer)

Supplier: Rockland Immunochemicals
Description: TE buffer is a commonly used buffer solution in molecular biology, especially in procedures involving DNA, cDNA or RNA. "TE" is derived from its components: Tris, a common pH buffer, and EDTA, a molecule that chelates cations like Mg2+. The purpose of TE buffer is to solubilize DNA or RNA, while protecting it from degradation.

Product Image-ROCKMB-019

Buffer, TBE solution 10X concentrate (TRIS-borate-EDTA buffer)

Catalog Number: (ROCKMB-019)
Supplier: Rockland Immunochemicals
Description: Running Buffer, TBE buffer solution 10X concentrate (TRIS-borate-EDTA buffer)
UOM: 1 * 1 L
Product Image-0780-50L

VWR® UltraPure, Phosphate buffered saline (PBS), powdered

Supplier: VWR Chemicals
Description: PBS, Ultra Pure Grade is a powdered, magnesium- and calcium-free formulation of PBS suitable for cell culture and for use in flow cytometry applications.

MSDS Certificates

Image Unavailable-BOSSBS-7720R-A680

Anti-DSCC1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-7720R-A680)
Supplier: Bioss
Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7720R-A750

Anti-DSCC1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-7720R-A750)
Supplier: Bioss
Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2007R-CY5.5

Anti-PCNA Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2007R-CY5.5)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2006R-CY7

Anti-PCNA-proliferation Marker Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2006R-CY7)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0754R-FITC

Anti-PCNA Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0754R-FITC)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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