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Image Unavailable-BOSSBS-2006R-A647

Anti-PCNA-proliferation Marker Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-2006R-A647)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Image Unavailable-ENZOADI801284

RIPA cell lysis buffer 2

Catalog Number: (ENZOADI801284)
Supplier: ENZO LIFE SCIENCES
Description: RIPA cell lysis buffer 2, Enzo Life Sciences
UOM: 1 * 100 mL
Image Unavailable-50033.

Fura 2-AM ≥98% (by HPLC) fluorescent indicator, for calcium determination

Supplier: Biotium
Description: Fura-2, AM ester is a ratiometric fluorescent dye that binds to free intracellular calcium, and is the preferred dye for ratiometric imaging microscopy. Fura-2, AM ester is membrane-permeant and thus can be loaded into cells via incubation.

Image Unavailable-50029.

Fura 2-AM 1 mM in anhydrous DMSO fluorescent indicator, for calcium determination

Catalog Number: (50029.)
Supplier: Biotium
Description: Fura-2, AM ester is a ratiometric fluorescent dye that binds to free intracellular calcium, and is the preferred dye for ratiometric imaging microscopy. Fura-2, AM ester is membrane-permeant and thus can be loaded into cells via incubation.
UOM: 1 * 1 mL
Product Image-ROCKMB-013

Tween-Tris-buffered saline (TTBS), 10X concentrate, pH 7,5

Catalog Number: (ROCKMB-013)
Supplier: Rockland Immunochemicals
Description: Tween Tris buffered saline is suitable for multiple applications including biological diluent buffer for antibodies or other biologics. Also may be used as a wash buffer for immunological assays including western blot, immunohistochemistry, immunofluorescence microscopy, and ELISA.
UOM: 1 * 1 L

Certificates


Image Unavailable-ABCAAB184093-100

Anti-alpha Tubulin Mouse Monoclonal Antibody [clone: DM1A] (Alexa Fluor® 680)

Catalog Number: (ABCAAB184093-100)
Supplier: Abcam
Description: Anti-alpha Tubulin Mouse Monoclonal Antibody [clone: DM1A] (Alexa Fluor® 680)
UOM: 1 * 100 µG
Image Unavailable-ABCAAB206908-100

Anti-Vinculin Rabbit Monoclonal Antibody [clone: EPR8185] (Alexa Fluor® 555)

Catalog Number: (ABCAAB206908-100)
Supplier: Abcam
Description: Anti-Vinculin Rabbit Monoclonal Antibody [clone: EPR8185] (Alexa Fluor® 555)
UOM: 1 * 100 µl
Product Image-MSGA41365

Safety Storage Cabinet, Type 90, ION-CORE-90 STORE model IO90.195.060.CS.WDC

Supplier: asecos
Description: Safe passive storage of lithium-ion batteries.

Image Unavailable-BOSSBS-2006R-CY5.5

Anti-PCNA-proliferation Marker Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2006R-CY5.5)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2007R-A750

Anti-PCNA [Proliferation Marker] Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-2007R-A750)
Supplier: Bioss
Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesise across the lesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7720R-CY5.5

Anti-DSCC1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7720R-CY5.5)
Supplier: Bioss
Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7720R-CY7

Anti-DSCC1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-7720R-CY7)
Supplier: Bioss
Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7720R-CY3

Anti-DSCC1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7720R-CY3)
Supplier: Bioss
Description: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
UOM: 1 * 100 µl
Image Unavailable-ABCAAB181602-1ML

Anti-GAPDH Rabbit Monoclonal Antibody [clone: EPR16891]

Catalog Number: (ABCAAB181602-1ML)
Supplier: Abcam
Description: Anti-GAPDH Rabbit Monoclonal Antibody [clone: EPR16891]
UOM: 1 * 1 mL

New Product


Image Unavailable-ABCAAB181603-1ML

Anti-GAPDH Rabbit Monoclonal Antibody [clone: EPR16884]

Catalog Number: (ABCAAB181603-1ML)
Supplier: Abcam
Description: Anti-GAPDH Rabbit Monoclonal Antibody [clone: EPR16884]
UOM: 1 * 1 mL

New Product


Product Image-M325-100ML

VWR®RapidBlock™, Blocking solution, 10x

Catalog Number: (M325-100ML)
Supplier: VWR Chemicals
Description: RapidBlock™ solution reduces blocking time to five minutes for Western and dot blotting procedures on PVDF and nitrocellulose membranes. This protein-free formulation minimises cross-reactivity and non specific antibody binding, generating blots with low background and enhanced signal-to-noise ratio.
UOM: 1 * 100 mL
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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