You Searched For: Lipopolysaccharides


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Catalog Number: (PRSI33-216)
Supplier: ProSci Inc.
Description: This antibody is specific for a 17-26 kDa protein, which is identified as the cytokine TNF alpha (Tumor Necrosis Factor alpha). It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. It is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. It exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
UOM: 1 * 100 µG


Catalog Number: (PRSI49-298)
Supplier: ProSci Inc.
Description: IL-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members. The cytoplasmic domains of TIR proteins interact with the adapter protein, MyD88. MyD88 then recruits IRAKs (IRAK-1, -2, and M), which in turn interact with other adapter molecules, such as TRAF6 to activate NF-κB and MAPK pathways. Recently, a new member of this family, IRAK-4 has been identified. IRAK-4 may act as an upstream activator of IRAK-1. IRAK-4 is important for LPS activation of TLRS. Mice lacking IRAK-4 are resistant to lethal doses of LPS and are also severely impaired in their responses to viral and bacterial challenges (4, 5). IRAK4, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK4 has auto- and cross-phosphorylation kinase activity and has been shown to phosphorylate and activate IRAK1. Additionally, IRAK4 interacts with IRAK1 and TRAF6 in an IL-1-dependent manner, and overexpression of IRAK4 can activate NF-kappaB as well as mitogen-activated protein (MAP) kinase pathways. IRAK4 (-/-) mice are resistant to a lethal dose of lipopolysaccharide and are severely impaired in their responses to viral and bacterial challenges. At least two mRNA transcripts have been reported: 3.0- and 4.4-kb. IRAK4, also referrred to as NY-REN-64, was first identified as an anitgen in a screen of renal tumors.
UOM: 1 * 50 µG


Catalog Number: (437650-5)
Supplier: Merck Millipore (Calbiochem‎)
Description: Lipopolysaccharide Salmonella Typhimurium 1 * 5 mg
UOM: 1 * 5 mg


Catalog Number: (437620-5)
Supplier: Merck Millipore (Calbiochem‎)
Description: Lipopolysaccharide E. Coli J5 1 * 5 mg
UOM: 1 * 5 mg


Catalog Number: (437628-1)
Supplier: Merck Millipore (Calbiochem‎)
Description: Lipopolysaccharide ultra pure salmonel 1 * 1 mg
UOM: 1 * 1 mg


Catalog Number: (437627-5)
Supplier: Merck Millipore (Calbiochem‎)
Description: Lipopolysaccharide E. Coli O111: B4 1 * 5 mg
UOM: 1 * 5 mg


Catalog Number: (ANTIA320875-25)
Supplier: ANTIBODIES.COM
Description: Synthetic DNA aptamer to Lipopolysaccharide [B2] (Biotin). 1 * 25 µG
UOM: 1 * 25 µG

New Product


Catalog Number: (USBI026552)
Supplier: US Biological
Description: Lipopolysaccharides (LPS) BioAssay ELISA Kit (Lipoglycan, Endotoxin) 1 * 96 Tests
UOM: 1 * 96 Tests


Catalog Number: (ANTIA4716-48)
Supplier: ANTIBODIES.COM
Description: Lipopolysaccharides ELISA Kit is a competitive Enzyme-Linked Immunosorbent Assay (cELISA) designed for the in vitro quantitative det ermination of Lipopolysaccharides in serum, plasma, tissue homogenates, cell lysates, cell culture supernates or othe 1 * 48 Tests
UOM: 1 * 48 Tests

New Product


Catalog Number: (ANTIA4716-96)
Supplier: ANTIBODIES.COM
Description: Lipopolysaccharides ELISA Kit is a competitive Enzyme-Linked Immunosorbent Assay (cELISA) designed for the in vitro quantitative det ermination of Lipopolysaccharides in serum, plasma, tissue homogenates, cell lysates, cell culture supernates or othe 1 * 96 Tests
UOM: 1 * 96 Tests

New Product


Catalog Number: (BSBTA00809-1)
Supplier: Boster Bio
Description: Rabbit IgG polyclonal antibody for Lipopolysaccharide-binding protein(LBP) detection. Tested with WB in Human Mouse Rat. 1 * 100 µG
UOM: 1 * 100 µG


Catalog Number: (AVIVARP41545_P050)
Supplier: Aviva Systems Biology
Description: Anti-LBP Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (AVIVARP41546_P050)
Supplier: Aviva Systems Biology
Description: Anti-LBP Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (USBIL2525-25F)
Supplier: US Biological
Description: Anti-LBP Rabbit Polyclonal Antibody
UOM: 1 * 100 µG


Catalog Number: (USBI129121)
Supplier: US Biological
Description: Anti-LITAF Mouse Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (USBIL2525-25B)
Supplier: US Biological
Description: Anti-LBP Rat Monoclonal Antibody [clone: 9G213]
UOM: 1 * 100 µG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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