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Image Unavailable-BOSSBS-6661R-A647

Anti-MIP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-6661R-A647)
Supplier: Bioss
Description: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80% of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12859R-A555

Anti-CRYBA1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-12859R-A555)
Supplier: Bioss
Description: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12859R-A488

Anti-CRYBA1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12859R-A488)
Supplier: Bioss
Description: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl
Image Unavailable-630-1045

Reading magnifier, combi-plus

Catalog Number: (630-1045)
Supplier: ESCHENBACH OPTIK
Description: Aspherical PXM® light-weight lens.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-13200R

Anti-FOXE3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13200R)
Supplier: Bioss
Description: This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11015R-A750

Anti-BFSP2/Phakinin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-11015R-A750)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10 nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Image Unavailable-MLDV6510-0002

Filters for microplate readers

Supplier: MOLECULAR DEVICES
Description: Filters for UVMax/ThermoMax microplate readers.

Product Image-630-1784

VWR® VisiScope®, Lenses for Stereo Microscopes

Supplier: VWR Collection
Description: Lens for stereo microscopes, VWR® VisiScope®, 2×, Working distance: 26 mm

Product Image-MMMASF203AFP

SecureFit™ 200 Safety Glasses

Supplier: 3M
Description: 3M™ SecureFit™ 200 series are lightweight safety glasses with 3M™ Pressure Diffusion Temple Technology. The glasses feature a wraparound design that’s secure and comfortable. They are available in various lens tints.

Product Image-JSPAASA480-0A7-600

Safety spectacle, Galactus™

Supplier: JSP
Description: Adaptable and ultra-light safety spectacle with base ten lens.

Image Unavailable-BOSSBS-11015R-A555

Anti-RPSA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11015R-A555)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11015R-CY3

Anti-RPSA Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11015R-CY3)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11015R-A350

Anti-RPSA Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11015R-A350)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Product Image-818-0281

VWR® B'Paper, Cleanroom paper

Supplier: VWR Collection
Description: Formulated with coated paper, without magnesium silicate, b-paper 80 or 92 g is cut, cleaned and packed in a Class 100 (ISO 5) cleanroom.

Product Image-630-8150

Reading magnifiers

Supplier: ESCHENBACH OPTIK
Description: This magnifier provides biconvex PXM® lightweight lens for an ergonomic use and optimised performances.

Product Image-STUA03013-61

Cole-Parmer® Stuart MP-100 Analogue Melting Point Apparatus

Catalog Number: (STUA03013-61)
Supplier: Cole Parmer
Description: Integral LED illumination and magnifying lens make viewing easy.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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