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Product Image-PRSI79-736

Anti-TRIM28 Rabbit Polyclonal Antibody

Catalog Number: (PRSI79-736)
Supplier: ProSci Inc.
Description: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger.
UOM: 1 * 100 µG
Image Unavailable-ERLAAB32A0333

Model technology: Filtering storage cabinet Captair 832BF Midcap Filters configuration: 1C Door: with shelves+single lock Power supp ly: GB Version: 3 1 * 1 items

Catalog Number: (ERLAAB32A0333)
Supplier: ERLAB CAPTAIRE
Description: Model technology: Filtering storage cabinet Captair 832BF Midcap Filters configuration: 1C Door: with shelves+single lock Power supp ly: GB Version: 3 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-BOSSBS-6414R-A750

Anti-CLLD8 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-6414R-A750)
Supplier: Bioss
Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1015R-FITC

Anti-BRMS1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1015R-FITC)
Supplier: Bioss
Description: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-HRP

Anti-ALKBH8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6510R-HRP)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-CY5

Anti-ALKBH8 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6510R-CY5)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-CY7

Anti-ALKBH8 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6510R-CY7)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1015R-CY7

Anti-BRMS1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1015R-CY7)
Supplier: Bioss
Description: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6414R-CY5.5

Anti-SETDB2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-6414R-CY5.5)
Supplier: Bioss
Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
UOM: 1 * 100 µl
Image Unavailable-ERLAAB32A0323

Model technology: Filtering storage cabinet Captair 832BF Midcap Filters configuration: 1C Door: with shelves+single lock Power supp ly: EU Version: 3 1 * 1 items

Catalog Number: (ERLAAB32A0323)
Supplier: ERLAB CAPTAIRE
Description: Model technology: Filtering storage cabinet Captair 832BF Midcap Filters configuration: 1C Door: with shelves+single lock Power supp ly: EU Version: 3 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-BOSSBS-6510R-CY5.5

Anti-ALKBH8 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-6510R-CY5.5)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-A350

Anti-ALKBH8 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-6510R-A350)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1015R-CY3

Anti-BRMS1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1015R-CY3)
Supplier: Bioss
Description: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R

Anti-ALKBH8 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-6510R)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6414R-HRP

Anti-SETDB2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6414R-HRP)
Supplier: Bioss
Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
UOM: 1 * 100 µl
Product Image-SELZHGPX4-5

Recombinant Human Glutathione Peroxidase 4

Supplier: SELENOZYME
Description: The human GPX4 selenoprotein is encoded by the GPX4 gene and has hydrogen peroxide and lipid hydroperoxide reducing activity using glutathione, protecting cells from ferroptosis.
We provide the human GPX4 enzyme with approx. 20% Sec contents, mixed with inactive forms containing Sec-to-Lys and Sec-to-Gln substitutions, at more than 95% purity in aliquots at amounts from 0,5 to 5 units.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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