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Image Unavailable-BOSSBS-6107R

Anti-HLTF Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-6107R)
Supplier: Bioss
Description: Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6414R-A350

Anti-SETDB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-6414R-A350)
Supplier: Bioss
Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3221R-FITC

Anti-CBX3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-3221R-FITC)
Supplier: Bioss
Description: HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7697R-A350

Anti-ZMYND11 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-7697R-A350)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7697R-HRP

Anti-ZMYND11 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-7697R-HRP)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7697R-A555

Anti-ZMYND11 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-7697R-A555)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6414R-CY7

Anti-SETDB2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6414R-CY7)
Supplier: Bioss
Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7697R-CY7

Anti-ZMYND11 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-7697R-CY7)
Supplier: Bioss
Description: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
UOM: 1 * 100 µl
Product Image-AATB5258

FMOC-Lys(TQ3)-OH for biomolecular labeling

Catalog Number: (AATB5258)
Supplier: AAT BIOQUEST
Description: FMOC-Lys(TQ3)-OH is a building block for in-sequence Lys labeling by Tide Quencher™ 3 (TQ3).
UOM: 1 * 100 mg
Product Image-AATB5020

Fmoc-Lys(biotin)-OH for biomolecular labeling

Catalog Number: (AATB5020)
Supplier: AAT BIOQUEST
Description: FMOC-Lys(Biotin)-OH is a lysine derivative for the preparation of biotin-labeled peptides by FMOC-SPPS.
UOM: 1 * 100 mg
Image Unavailable-USBIB2727-01E

Anti-BRCC3 Mouse monoclonal antibody unconjugated [clone: AT3B1]

Catalog Number: (USBIB2727-01E)
Supplier: US Biological
Description: Anti-BRCC3 Mouse monoclonal antibody unconjugated [clone: AT3B1]
UOM: 1 * 50 µl
Product Image-AATB5260

FMOC-Lys(QSY-21)-OH for biomolecular labeling

Catalog Number: (AATB5260)
Supplier: AAT BIOQUEST
Description: FMOC-Lys(QSY-21)-OH is a building block for in-sequence Lys labeling by QSY-21.
UOM: 1 * 50 mg
Image Unavailable-BOSSBS-10030R-CY7

Anti-LEO1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-10030R-CY7)
Supplier: Bioss
Description: Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Involved in polyadenylation of mRNA precursors. Connects PAF1C to Wnt signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6414R-A488

Anti-SETDB2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-6414R-A488)
Supplier: Bioss
Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-A750

Anti-ABH8 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-6510R-A750)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-FITC

Anti-ALKBH8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-6510R-FITC)
Supplier: Bioss
Description: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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