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Product Image-LEIF56415

Supra Rubber Broom

Catalog Number: (LEIF56415)
Supplier: LEIFHEIT AG
Description: Made from natural rubber. Whether sweeping, scrubbing or brushing, this broom cleans all floors, both indoors and outdoors.
UOM: 1 * 1 items

New Product


Image Unavailable-1.01502.0100

Silver, Patinal®

Catalog Number: (1.01502.0100)
Supplier: Merck
Description: Silver, Patinal®
UOM: 1 * 100 g

MSDS


Automated plate washing for ELISA, cells and beads

Improve lab efficiency & optimize results with fast and efficient plate washers. Compare and find the optimal plate washer for your applications.

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TECAN microplate washers

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Image Unavailable-ENZOBMLEI2580005

AG-879 ≥99%

Supplier: ENZO LIFE SCIENCES AG
Description: NGF receptor inhibitor

New Product

Image Unavailable-1.19208.0025

Silver(I) oxide, Supelco®

Supplier: Merck
Description: Silver(I) oxide, Supelco®

MSDS

Image Unavailable-1.01506.0010

Silver ≥99.9%, wool for elementary analysis, Supelco®

Catalog Number: (1.01506.0010)
Supplier: Merck
Description: Silver ≥99.9%, wool for elementary analysis, Supelco®
UOM: 1 * 10 g

MSDS


Image Unavailable-ENZOBMLEI2280010

AG-494 ≥98% (by TLC)

Catalog Number: (ENZOBMLEI2280010)
Supplier: ENZO LIFE SCIENCES AG
Description: AG-494 is a member of the tyrphostin family of tyrosine kinase inhibitors and is a potent inhibitor of EGF receptor autophosphorylation (IC50=1.2 µM) and EGF-dependent cell growth (IC50=6 µM). It selectively inhibits HER1 (EGF receptor) vs. HER1-2 receptor autophosphorylation (HER1: IC50=1.1 µM; HER1-2: IC50=45 µM). HER1-2 is a chimeric receptor consisting of the external HER1 domain fused to an internal HER2 domain. Blocks CDK2 activation and causescells to arrest at late G1 and during S phase.
UOM: 1 * 10 mg

New Product


Image Unavailable-APOSBISN0202-5MG

Tyrphostin AG-126

Supplier: Apollo Scientific
Description: MAPK/ERK Signalling Pathway

Image Unavailable-ENZOBMLEI3350050

AG-1288 ≥98% (by TLC)

Catalog Number: (ENZOBMLEI3350050)
Supplier: ENZO LIFE SCIENCES AG
Description: Tyrosine kinase inhibitor. It has been shown to block TNFα induced cytotoxicity and to block glucocorticoid-induced COX-2 activity in human amnion cells (IC50=21μM). It is also reported to inhibit guanylyl cyclase.
UOM: 1 * 50 mg

New Product


Product Image-ENZOALX270141M025

Tyrphostin AG 527 ≥98% (by HPLC)

Catalog Number: (ENZOALX270141M025)
Supplier: ENZO LIFE SCIENCES AG
Description: Tyrphostin AG 527 ≥98% (by HPLC)
UOM: 1 * 25 mg

New Product


Image Unavailable-ENZOBMLEI2630025

Tyrphostin AG-126 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG
Description: AG-126 prevents lipopolysaccharide-induced lethal toxicity (septic shock) in mice. Administered at 1.5 mg/mouse, it reduced LPS-induced lethal toxicity from 95% to 10%. AG-126 greatly reduces LPS-induced tyrosine phosphorylation of p42MAPK in murine peritoneal macrophages at 50 µM. EGFR, Her-2/neu receptor or PDGF-R are not inhibited at 100 µM. Inhibits tyrosine kinase-dependent B cell receptor signaling.

New Product

Image Unavailable-ENZOBMLEI1890005

Tyrphostin AG 183 ≥99%

Catalog Number: (ENZOBMLEI1890005)
Supplier: ENZO LIFE SCIENCES AG
Description: A potent inhibitor of EGF receptor kinase activity (IC50=0.8 µM). Inhibition is mixed competitive with ATP and substrate.
UOM: 1 * 5 mg

New Product


Product Image-21584.134

Silver(I) oxide ≥99%, TECHNICAL

Catalog Number: (21584.134)
Supplier: VWR Chemicals
Description: Silver(I) oxide ≥99%, TECHNICAL
UOM: 1 * 25 g

MSDS Certificates


Image Unavailable-ENZOBMLEI2720010

Tyrphostin AG 490 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES AG
Description: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

New Product

Image Unavailable-APOSBIT1101-25MG

Tyrphostin AG 1478 free base 99+%

Supplier: Apollo Scientific
Description: Very potent EGF receptor kinase (tyrosine kinase) inhibitor (IC50 = 3 nM). Very weak on PDGF receptor and HER2-NEU kinases (IC50 >100 uM). Eur. J. Biochem. 225: 1047-1053 (1994).

Image Unavailable-1.01534.0050

Silver sulphate, Supelco®

Supplier: Merck
Description: Silver sulphate, Supelco®

MSDS

Image Unavailable-ENZOALX270217M005

Tyrphostin AG 1024 ≥98% (by HPLC and UV method)

Supplier: ENZO LIFE SCIENCES AG
Description: Specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor kinases. Induces apoptosis by downregulation of the expression of phospho-Akt1 and Bcl-2. Also increases Bax, p53 and p21 expression.

New Product

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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