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Catalog Number: (BOSSBS-13654R-A680)
Supplier: Bioss
Description: Several mammalian kinases have been identified with sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase STE20. STE20 is involved in relaying signals from G-protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include KHS, GLK, NIK, YSK1, HPK1, Krs-1, Krs-2 and GC kinase. KHS (for kinase homologous to SPS1/STE20) is a protein that is most closely related to GC kinase. The KHS kinase has been shown to activate a variety of substrates, including JNK, suggesting a role in stress response.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1528R-A350)
Supplier: Bioss
Description: Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11544R-A750)
Supplier: Bioss
Description: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukaemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukaemia, and may function as a leukaemia disease gene, in part, through its interaction with Bcl-6.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-11544R-A680)
Supplier: Bioss
Description: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukaemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukaemia, and may function as a leukaemia disease gene, in part, through its interaction with Bcl-6.
UOM: 1 * 100 µl


Catalog Number: (ZEIS4208529872799)
Supplier: ZEISS
Description: Imm Korr DIC M27 1 * 1 items
UOM: 1 * 1 items

New Product


Catalog Number: (SEMA0023)
Supplier: SEMADENI
Description: BOTTLE DROPPER LDPE 50 ML 1 * 1 items
UOM: 1 * 1 items


Catalog Number: (SEMA2621)
Supplier: SEMADENI
Description: PLUG LDPE Ø 55 MM 1 * 100 items
UOM: 1 * 100 items


Catalog Number: (SEMA2609)
Supplier: SEMADENI
Description: PLUG LDPE Ø 425 MM 1 * 100 items
UOM: 1 * 100 items


Catalog Number: (TAYW6913-9046)
Supplier: TAYLOR WHARTON
Description: 15 PSI RELIEF VALVE6913-9046 (FOR LDW) 1 * 1 items
UOM: 1 * 1 items


Catalog Number: (BURK0303-0050)
Supplier: BURKLE
Description: Narrow-necked bio-bottles PE, Green LDPE, 50 ml 1 * 1 items
UOM: 1 * 1 items


Catalog Number: (SEMA3492)
Supplier: SEMADENI
Description: PLUG HOLE LDPE 16.5 TO 18 MM Ø 1 * 100 items
UOM: 1 * 100 items


Catalog Number: (SEMA1519)
Supplier: SEMADENI
Description: BLADEPLUG LDPE Ø 25 MM 1 * 100 items
UOM: 1 * 100 items


Catalog Number: (SEMAF024212)
Supplier: SEMADENI
Description: FLEXICO MINIGRIP® PE MAXI 100µ 80X120 1 * 500 items
UOM: 1 * 500 items


Catalog Number: (SEMA6331)
Supplier: SEMADENI
Description: SPRAY BOTTLE 250ML YELLOW (LDPE) 1 * 1 items
UOM: 1 * 1 items


Catalog Number: (SEMA1494)
Supplier: SEMADENI
Description: PLUG LDPE Ø 35 MM 1 * 100 items
UOM: 1 * 100 items


Catalog Number: (SEMA1493)
Supplier: SEMADENI
Description: PLUG LDPE Ø 34 MM 1 * 100 items
UOM: 1 * 100 items


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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