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Image Unavailable-MSPPHD119

HD black ink cartridge 1 * 1 items

Catalog Number: (MSPPHD119)
Supplier: MARKET SOURCE PART PROCESS
Description: HD black ink cartridge 1 * 1 items
UOM: 1 * 1 items

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-BSENC-1691-100

Anti-MAPT Chicken Polyclonal Antibody

Catalog Number: (BSENC-1691-100)
Supplier: Biosensis
Description: FUNCTION: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. SUBCELLULAR LOCATION: Cytoplasm; cytosol. Cell membrane. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. ALTERNATIVE PRODUCTS: 8 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Isoforms differ from each other by the presence or absence of up to 5 of the 15 exons. One of these optional exons contains the additional tau/MAP repeat. TISSUE SPECIFICITY: Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. DEVELOPMENTAL STAGE: Four-repeat (type II) tau is expressed in an adult-specific manner and is not found in fetal brain, whereas three-repeat (type I) tau is found in both adult and fetal brain. DOMAIN: The tau/MAP repeat binds to tubulin. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments and straight filaments, mainly composed of hyperphosphorylated forms of Microtubule-associated protein Tau. Defects in Microtubule-associated protein Tau are a cause of frontotemporal dementia and parkinsonism linked to chromosome 17, as well as a number of other neurodegenerative diseases.
UOM: 1 * 100 µl
Image Unavailable-MSPP78253

Trodat Printy Ink Cartridges 6/4750 [2PK Color Replacement Ink Cartridge] 1 * 2 items

Catalog Number: (MSPP78253)
Supplier: MARKET SOURCE PART PROCESS
Description: Trodat Printy Ink Cartridges 6/4750 [2PK Color Replacement Ink Cartridge] 1 * 2 items
UOM: 1 * 2 items

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-RADS340-8441

PEN LABELLING S 1 * 1 Each

Catalog Number: (RADS340-8441)
Supplier: RADIONICS
Description: PEN LABELLING S 1 * 1 Each
UOM: 1 * 1 Each
Image Unavailable-MSPPV435-D

VIDEOJET INK BLACK 1 * 750 mL

Catalog Number: (MSPPV435-D)
Supplier: MARKET SOURCE PART PROCESS
Description: VIDEOJET INK BLACK 1 * 750 mL
UOM: 1 * 750 mL

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-LAUDHOB014

INK CART FOR LASERJET 5L S 1 * 1 items

Catalog Number: (LAUDHOB014)
Supplier: LAUDA
Description: INK CART FOR LASERJET 5L S 1 * 1 items
UOM: 1 * 1 items
Product Image-BSENM-1703-100

Anti-Microtubule-associated Protein tau Mouse Monoclonal Antibody [clone: B2E9]

Catalog Number: (BSENM-1703-100)
Supplier: Biosensis
Description: FUNCTION: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.  SUBCELLULAR LOCATION: Cytoplasm; cytosol. Cell membrane. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. ALTERNATIVE PRODUCTS: 8 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Isoforms differ from each other by the presence or absence of up to 5 of the 15 exons. One of these optional exons contains the additional tau/MAP repeat. TISSUE SPECIFICITY: Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. DEVELOPMENTAL STAGE: Four-repeat (type II) tau is expressed in an adult-specific manner and is not found in fetal brain, whereas three-repeat (type I) tau is found in both adult and fetal brain. DOMAIN: The tau/MAP repeat binds to tubulin. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments  and straight filaments, mainly composed of hyperphosphorylated forms of Microtubule-associated protein Tau. Defects in Microtubule-associated protein Tau are a cause of frontotemporal dementia and parkinsonism linked to chromosome 17, as well as a number of other neurodegenerative diseases.
UOM: 1 * 100 µl
Image Unavailable-RADS425-9379

flux pen S 1 * 1 Each

Catalog Number: (RADS425-9379)
Supplier: RADIONICS
Description: flux pen S 1 * 1 Each
UOM: 1 * 1 Each
Image Unavailable-IBSAP100M/0056

GREEN PENS 1 * 3 items

Catalog Number: (IBSAP100M/0056)
Supplier: IBS Stock Items
Description: GREEN PENS 1 * 3 items
UOM: 1 * 3 items
Image Unavailable-RADS199-5173

PEN KNIFE S 1 * 1 Each

Catalog Number: (RADS199-5173)
Supplier: RADIONICS
Description: PEN KNIFE S 1 * 1 Each
UOM: 1 * 1 Each
Image Unavailable-STERP117026048

CARTRIDGE SUB INK BLACK 1 * 1 items

Catalog Number: (STERP117026048)
Supplier: STERIS
Description: CARTRIDGE SUB INK BLACK 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-BELENA0444

INK CARTRIDGE FOR TX-110 1 * 1 items

Catalog Number: (BELENA0444)
Supplier: BEL ENGINEERING
Description: INK CARTRIDGE FOR TX-110 1 * 1 items
UOM: 1 * 1 items

New Product


Image Unavailable-HEWLG1530-67050

INK Blnk Cover/Insul 1 * 1 items

Catalog Number: (HEWLG1530-67050)
Supplier: Agilent
Description: INK Blnk Cover/Insul 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-HEWLG1833-65519

COVER FOR THE PENNING 1 * 1 items

Catalog Number: (HEWLG1833-65519)
Supplier: Agilent
Description: COVER FOR THE PENNING 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-DICKP226

PENS REPLACEMENT BLUE 1 * 6 items

Catalog Number: (DICKP226)
Supplier: DICKSON
Description: PENS REPLACEMENT BLUE 1 * 6 items
UOM: 1 * 6 items
Image Unavailable-SLEE10040001

MANUAL SLIDE MICROTOME CUTTEC S INK 1 * 1 items

Catalog Number: (SLEE10040001)
Supplier: Slee
Description: MANUAL SLIDE MICROTOME CUTTEC S INK 1 * 1 items
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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