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Product Image-PRSI36-346

Anti-VASP Rabbit Polyclonal Antibody

Catalog Number: (PRSI36-346)
Supplier: ProSci Inc.
Description: VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.
UOM: 1 * 25 µG
Product Image-PRSI36-349

Anti-VASP Rabbit Polyclonal Antibody

Catalog Number: (PRSI36-349)
Supplier: ProSci Inc.
Description: VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.
UOM: 1 * 100 µl
Product Image-710-0748

Culture media solutions, TransFast® system

Supplier: DOEHLER GROUP
Description: Fast and easy detection of beverage spoiling microorganisms. Qualitative detection of yeast, moulds, and lactic and acetic acid bacteria in beverages at pH <4,5 in under 48 hours.

Certificates

Product Image-461-0883

Refrigerated/heating circulators, CORIO™ CD series

Supplier: JULABO GmbH
Description: These powerful and robust CORIO™ laboratory circulators provide the exact temperature, absolute precision and a wide working temperature range. The CORIO™ CD controller is an advanced unit with professional technology for demanding applications and can be used for temperature control of internal or external applications. The jet nozzle allows continuous adjustment of the pump stream in the system. The insulated stainless steel baths are durable and have an integrated drain tap. These heating/cooling circulators are ideal for temperature control of samples in a circulator bath or temperature control of an external application. For example: Measuring cells, refractometers, polarimeters, photometers, viscometers, fermenters, electrophoresis chambers, chromatography columns, rotary evaporators and rheometers.

Environmentally Preferable

Product Image-COPA414C

Copan Transystem® Traditional Swab Collection and Transport System for Aerobic and Anaerobic Bacteria

Supplier: Copan
Description: <p>Our Transystem™ family comprises different media for the efficient and safe transport of many bacterial strains. Choose between liquid or solid Amies and Stuart medium for aerobic culture, rapid antigen, and molecular testing; opt for gel Cary-Blair medium - with or without charcoal - for aerobic and anaerobic cultures. Bacterial transport basics. A simple, low bioburden, device for every investigation. Just uncap, collect and recap the tube.</p>

Certificates

Product Image-SCAA565200

Tork S5 Mini Soap and Sanitiser Dispensers

Supplier: Essity
Description: <p>Meet multiple hygiene needs with one system - wide range of soaps and sanitiser refills in foam, liquid, gel or lotion to suit the business and user's needs.</p>

New Product

Image Unavailable-PRSI33-834

Anti-KRT1, KRT3, KRT4, KRT5, KRT6A, KRT8, KRT10, KRT14, KRT15, KRT16, KRT19 Rabbit Polyclonal Antibody

Catalog Number: (PRSI33-834)
Supplier: ProSci Inc.
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody detects acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins: 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
UOM: 1 * 100 µG

New Product


Product Image-481-0426

Autoclaves, LABOKLAV

Supplier: SHP Steriltechnik
Description: A completely new concept allows the installation of the unit as either front or top loader. Deciding on horizontal or vertical is no longer the question with SHP autoclaves. No matter if installed horizontally or vertically, the units remain the same. Even at a later stage the unit can be changed from vertical to horizontal installation or vice versa without the need for big technical changes (contact Avantor for details). When set up as horizontal units they are even stackable. Stainless steel 316L chamber and housing.

Product Image-700-0416

VWR® kuroGEL, Semi-dry blotter

Catalog Number: (700-0416)
Supplier: VWR Collection
Description: The kuroGEL semi-dry blotter provides great flexibility in a laboratory since it can be used for all types of blotting: Western, Southern and Northern. Blotting is fast and easy, and can typically be completed in 15 to 30 min. Set-up procedures are easy and economical with little buffer needed. The screw down lid adjusts to varying gel thicknesses and sizes, while the platinum coated electrodes provide uniform pressure ensuring even transfers.
UOM: 1 * 1 items
Product Image-481-0914

Autoclaves, medium capacity, Priorclave

Supplier: Priorclave
Description: These versatile autoclaves are fully equipped for use in laboratories throughout the food, drink, dairy, health and pharmaceutical industries and offer a wide range of options and accessories to further improve their performance to suit individual load types. This flexibility is enhanced by the TACTROL™ microprocessor control system, specially developed for laboratory autoclaves, with progamming ranging from simple cycles to fully featured multi-program operation with logged records. All Priorclaves come complete with Biomaster antimicrobial coating, helping improved laboratory hygiene; it is effective against all bacteria and fungi including MRSA and therefore helps minimise the risk of cross contamination.

Image Unavailable-ICNA04856126

Dithiothreitol (DTT, Cleland's reagent) ≥99.5%, white powder for electrophoresis

Catalog Number: (ICNA04856126)
Supplier: MP Biomedicals
Description: DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes. Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol.
Useful for stabilizing sulfhydryl-containing enzymes.
UOM: 1 * 5 g

Certificates


Image Unavailable-UVPA38-0221-01

Accessories for BioDoc-It and PhotoDoc-It

Supplier: UVP ULTRA VIOLET PRODUCTS
Description: Photodocumentation System, Gel tray (270×230 mm)

Image Unavailable-PIERA36368

High Select™ HSA/immunoglobulin depletion resin

Catalog Number: (PIERA36368)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific™ High Select HSA/Immunoglobulin Depletion Resin decreases the albumin and antibody components that are abundant in human plasma samples, helping prepare the samples for mass spectrometry or 1D or 2D electrophoresis.
UOM: 1 * 50 mL
Product Image-PIER89875

Albumin/IgG removal kit, Pierce™

Catalog Number: (PIER89875)
Supplier: Thermo Fisher Scientific
Description: The Pierce™ Albumin/IgG Removal Kit is optimised to decrease the abundant albumin and antibody components of human serum samples in preparation for 2D electrophoresis and other protein profiling methods. By eliminating most of these two proteins, which account for nearly 70% of total serum proteins, other less abundant proteins of interest can be more easily detected and studied.
UOM: 1 * 1 KIT
Image Unavailable-PIERA36372

High Select™ top14 abundant protein depletion resin, Pierce™

Catalog Number: (PIERA36372)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific™ High Select Top14 Abundant Protein Depletion Resin decreases the abundant protein and antibody components of human plasma samples, helping prepare the samples for mass spectrometry or 1D or 2D electrophoresis.
UOM: 1 * 50 mL

Certificates


Image Unavailable-ICNA02103130.1

TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99%, Reagent Grade

Supplier: MP Biomedicals
Description: Tris and Tris Hydrochloride have been useful as buffers in a wide variety of biological systems. Uses include pH control<i> in vitro </i>and <i>in vivo</i> for body fluids and in buffering systems for electrophoresis applications.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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