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Product Image-630-2157

Upright microscopes, BA410 Elite

Description: The BA410 Elite is designed for diagnosis in pathology, haematology and cytology.
Catalog Number: 630-2157
UOM: 1 * 1 items
Supplier: MOTIC
Image Unavailable-BOSSBS-11072R-A647

Anti-ASTN2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
Catalog Number: BOSSBS-11072R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11072R-A750

Anti-ASTN2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Neuronal migration of the central nervous system is a specialised form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
Catalog Number: BOSSBS-11072R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11072R-FITC

Anti-ASTN2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
Catalog Number: BOSSBS-11072R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10392R-A488

Anti-SYNGAP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
Catalog Number: BOSSBS-10392R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-15047R-FITC

Anti-C1orf187 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
Catalog Number: BOSSBS-15047R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10392R-FITC

Anti-SYNGAP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
Catalog Number: BOSSBS-10392R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10392R-A555

Anti-SYNGAP Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
Catalog Number: BOSSBS-10392R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-201-1419

Ramsbottom coking bulb

Description: Ramsbottom coking bulbs are used in the determination of carbon residue in petroleum products.
Catalog Number: 201-1419
UOM: 1 * 25 items
Supplier: DWK Life Sciences
Image Unavailable-BOSSBS-15047R-A750

Anti-C1orf187 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
Catalog Number: BOSSBS-15047R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-15047R-CY7

Anti-C1orf187 Rabbit Polyclonal Antibody (Cy7®)

Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
Catalog Number: BOSSBS-15047R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-PERCL6022728

Deuterium lamp, TruLife™ 1,5

Description: These deuterium lamps provide the best wavelength coverage across the working range of the spectrometer for consistently high performance.
Catalog Number: PERCL6022728
UOM: 1 * 1 items
Supplier: PerkinElmer
Image Unavailable-BOSSBS-2743R-CY7

Anti-SLIT2 Rabbit Polyclonal Antibody (Cy7®)

Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
Catalog Number: BOSSBS-2743R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-2743R-A350

Anti-SLIT2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
Catalog Number: BOSSBS-2743R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-630-3443

Biological microscopes, fixed Koehler halogen and LED, BA 210 Elite

Description: Microscope for basic work in biology life science. Fixed Koehler set-up, rackless stage, nice plan achromatic optics. The Motic BA 210 is robust and ready to use with pre-installed set-up of optics and halogen illumination, interchangeable with a LED module (LED to be purchased separately).
Catalog Number: 630-3443
UOM: 1 * 1 items
Supplier: MOTIC
Product Image-DIDAPOD068440

Spectral lamps, OSRAM

Description: Nine pin socket spectral lamps with dimensions (H×Ø) 107×21 mm, operated with 1 Amp fixed current.
Catalog Number: DIDAPOD068440
UOM: 1 * 1 items
Supplier: DIDALAB
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