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Specimen container, prefilled with 10% neutral buffered formalin, HistoTainer™

Catalog Number: (SIMPM961-120FW)

Supplier: Simport Scientific

Description: The HistoTainer™ is half filled with 10% neutral buffered formalin as a fixative, this penetrates quickly, but fixes slowly. The formalin is enhanced by a buffering capacity optimising histological results by light microscopy and immunohistochemistry.

UOM: 1 * 96 items

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Containers with snap caps, Corning® Gosselin™

Supplier: Corning

Description: These containers are made of transparent or white PP.

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Sample container, with screw cap

Supplier: DELTALAB

Description: These PP sample containers are ideal for pneumatic transport of specimens with high safety closure biflex caps.

Anti-KLH Mouse Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0225M-HRP)

Supplier: Bioss

Description: Keyhole limpet hemocyanin is an extremely large, heterogeneous glycosylated protein consisting of subunits with a molecular weight of 350,000 and 390,000 in aggregates with molecular weights of 4,500,000-13,000,000. Each domain of a KLH subunit contains two copper atoms that together bind a single oxygen molecule (O2). When oxygen is bound to hemocyanin, the molecule takes on a distinctive transparent, opalescent blue color. The KLH protein is potently immunogenic yet safe in humans and is therefore highly prized as a vaccine carrier protein. The large and highly glycosylated KLH protein cannot be reproduced synthetically. It is available only as a purified biological product from the Keyhole Limpet Megathura crenulata.Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein in the production of for research, biotechnology and therapeutic applications. Haptens are substances with a low molecular weight such as peptides, small proteins and drug molecules that are generally not immunogenic and require the aid of a carrier protein to stimulate a response from the immune system in the form of antibody production.[2] KLH is the most widely employed carrier proteins for this purpose. KLH is an effective carrier protein for several reasons. Its large size and numerous epitopes generate a substantial immune response, and abundance of lysine residues for coupling haptens, allows a high hapten:carrier protein ratio increasing the likelihood of generating hapten-specific . In addition, because KLH is derived from the limpet, a gastropod, it is phylogenetically distant from mammalian proteins, thus reducing false positives in immunologically based research techniques in mammalian model organisms.KLH may also be a challenging molecule to work with because of its propensity to aggregate and precipitate. Aggregates remain immunogenic, but limit the ability to conjugate haptens and are difficult to manipulate in the laboratory.

UOM: 1 * 100 µl

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