You Searched For: Gemcitabine+hydrochloride

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Anti-IER3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-6840R-A647)

Supplier: Bioss

Description: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

UOM: 1 * 100 µl

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Anti-IER3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-6840R-A350)

Supplier: Bioss

UOM: 1 * 100 µl

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Organic reference standards, gemcitabines, Ph. Eur.

Catalog Number: (EDQMY0001682)

Supplier: EDQM

Description: Organic Standard, Gemcitabine impurity C, 1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)pyrimidin-2,4(1H,3H)-dione (2′-deoxy-2′,2′-difluorouridine) (β-uridine), Ph. Eur. standard

UOM: 1 * 25 mg

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Anti-PNAS4 Rabbit Polyclonal Antibody

Catalog Number: (PRSI5217)

Supplier: ProSci Inc.

Description: PNAS4 Antibody: PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.

UOM: 1 * 100 µG

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