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Supplier: GLEN DIMPLEX
Description: For safe storage of vaccines, insulin and general drugs in pharmacies, hospital wards, clinics, surgeries, nursing homes and veterinary dispensaries. With storage bin.

Catalog Number: (BOSSBS-6634R-A680)
Supplier: Bioss
Description: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl


Catalog Number: (PRSI28-490)
Supplier: ProSci Inc.
Description: DDX42 is a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX42 is a ATP-dependent RNA helicase. DDX42 binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. It also mediates RNA duplex formation thereby displacing the single-strand RNA binding protein.This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.
UOM: 1 * 50 µG


Catalog Number: (471-0837)
Supplier: GLEN DIMPLEX
Description: Lec laboratory spark-free freezers offer safe, reliable storage of volatile liquids, reagents, poisons and samples. They have spark-free interiors to reduce the risk of internal explosions, CFC- and HCFC-free refrigeration systems ensuring minimal risk to the environment and locks to prevent theft or unauthorised access.
UOM: 1 * 1 items


Catalog Number: (VWRI510-815)
Supplier: VWR Collection
Description: KIT DUPLEX MOTOR AD/AP/PD/PP 240V 1 * 1 items
UOM: 1 * 1 items


Catalog Number: (ORIGSR30003)
Supplier: OriGene
Description: Trilencer-27 HPRT Positive control siRNA duplex - 1 nmol 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR307922)
Supplier: OriGene
Description: AZI1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 22994) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR300741)
Supplier: OriGene
Description: CDKN1B (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 1027) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR411257)
Supplier: OriGene
Description: 2610529C04Rik (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 67075) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR306022)
Supplier: OriGene
Description: LATS1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 9113) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR401535)
Supplier: OriGene
Description: S100a9 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 20202) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR300445)
Supplier: OriGene
Description: BMI1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 648) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR408864)
Supplier: OriGene
Description: Cdk4 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 12567) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR308858)
Supplier: OriGene
Description: LATS2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 26524) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR423588)
Supplier: OriGene
Description: Ubr5 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 70790) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


Catalog Number: (ORIGSR421961)
Supplier: OriGene
Description: Ret (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 19713) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
UOM: 1 * 1 KIT


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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