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Image Unavailable-PRSI91-320

Human recombinant IGF Binding 4 (from cells)

Catalog Number: (PRSI91-320)
Supplier: ProSci Inc.
Description: IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.
UOM: 1 * 50 µG
Product Image-PRSI32-191

Anti-MCL1 Mouse Monoclonal Antibody

Catalog Number: (PRSI32-191)
Supplier: ProSci Inc.
Description: Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.
UOM: 1 * 100 µG
Product Image-PRSI5453

Anti-FRMPD1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI5453)
Supplier: ProSci Inc.
Description: FRMPD1 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50% and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.
UOM: 1 * 100 µG
Image Unavailable-344273-5

Forskolin 7-Deacetyl-7-(O-N-Methylpiperazino)-G-Bu 1 * 5 mg

Catalog Number: (344273-5)
Supplier: Merck Millipore (Calbiochem‎)
Description: Forskolin 7-Deacetyl-7-(O-N-Methylpiperazino)-G-Bu 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-344282-5MG

FORSKOLIN COLEUS FORSKOHLII IN DMSO 1 * 5 mg

Catalog Number: (344282-5MG)
Supplier: Merck Millipore (Calbiochem‎)
Description: FORSKOLIN COLEUS FORSKOHLII IN DMSO 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-344273-10

Forskolin 7-Deacetyl-7-(O-N-Methylpiperazino)-G-Bu 1 * 10 mg

Catalog Number: (344273-10)
Supplier: Merck Millipore (Calbiochem‎)
Description: Forskolin 7-Deacetyl-7-(O-N-Methylpiperazino)-G-Bu 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-ICNA0219066925

FORSKOLIN. From Coleus forskohlii (7#-acetoxy-8,13-epoxy-1a,6# ,9a-trihydroxy-labd-14-ene-11-one)Reported to demonstrate positive ino tropic and heart rate-increasing activity at low doses in animals. 1 * 25 mg

Catalog Number: (ICNA0219066925)
Supplier: MP Biomedicals
Description: FORSKOLIN. From Coleus forskohlii (7#-acetoxy-8,13-epoxy-1a,6# ,9a-trihydroxy-labd-14-ene-11-one)Reported to demonstrate positive ino tropic and heart rate-increasing activity at low doses in animals. 1 * 25 mg
UOM: 1 * 25 mg
Product Image-ENZOBMLCN1050005

L-858051 ≥92% (by HPLC)

Catalog Number: (ENZOBMLCN1050005)
Supplier: Enzo Life Sciences
Description: Adenylate cyclase activator.
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLEI2680001

KN-93 ≥95% (by TLC)

Catalog Number: (ENZOBMLEI2680001)
Supplier: Enzo Life Sciences
Description: CaM kinase inhibitor
UOM: 1 * 1 mg
Image Unavailable-ENZOALX430127M005

KN-93 phosphate ≥98% (by 1H-NMR)

Supplier: Enzo Life Sciences
Description: CaM kinase II inhibitor

Image Unavailable-J63916.MB

Phorbol-12-myristate-13-acetate 95%

Supplier: Thermo Fisher Scientific
Description: Phorbol-12-myristate-13-acetate 95%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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