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You Searched For: Dihexyl+disulphide


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Image Unavailable-BOSSBS-4250R-FITC

Anti-PDIA2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-4250R-FITC)
Supplier: Bioss
Description: The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4250R-HRP

Anti-PDIA2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-4250R-HRP)
Supplier: Bioss
Description: The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4250R-A680

Anti-PDIA2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-4250R-A680)
Supplier: Bioss
Description: The three dimensional structure of many extracellular proteins is stabilised by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
UOM: 1 * 100 µl
Image Unavailable-H55807.03

2,2'-Dithiodianiline (thulium ionophore I) 97%

Supplier: Thermo Fisher Scientific
Description: 2,2'-Dithiodianiline (thulium ionophore I) 97%

MSDS

Image Unavailable-APOSBISN0322-5G

Disulphiram

Supplier: Apollo Scientific
Description: Disulphiram

Image Unavailable-B20721.30

Disulphiram ≥97%

Supplier: Thermo Fisher Scientific
Description: Disulphiram ≥97%

MSDS Certificates

Image Unavailable-ENZOADISPA891PED

Anti-PDI Mouse Monoclonal Antibody (PE (Phycoerythrin))

Supplier: ENZO LIFE SCIENCES
Description: The mammalian protein disulphide-isomerase (PDI) family encompasses several highly divergent proteins involved in the processing and maturation of secretory proteins in the ER by catalyzing the rearrangement of disulphide bonds. PDI, an abundant protein of the ER (>400uM), contains a carboxy-terminal retention signal sequence, KDEL, similar to that of BiP and Grp94. The PDI proteins are characterized by the presence of one or more domains of ~95-110 amino acids related to the cytoplasmic protein thioredoxin. All but the PDI-D subfamily are composed entirely of repeats of such domains, with at least one domain containing - and one domain lacking - a redox-active-Cys-X-X-Cys-tetrapeptide. In addition to roles as redox catalysts and isomerases, PDI proteins perform such functions as peptide binding and cell adhesion, and may conduct chaperone activities. Platelet surface thiols and disulphides play an important role in platelet responses. Catalytically active PDI resides on platelet surfaces where it mediates platelet aggregation and secretion by reducing disulfide bonds, thus exposing fibrinogen receptors in platelets.

Product Image-ACRO138480050

Thiram 97%

Supplier: Thermo Fisher Scientific
Description: Thiram 97%

MSDS

Image Unavailable-12213.A1

Molybdenum(IV) sulphide ≥98%

Supplier: Thermo Fisher Scientific
Description: Molybdenum(IV) sulphide ≥98%

MSDS Certificates

Image Unavailable-12826.06

Titanium(IV) sulphide ≥99.8% (metals basis)

Supplier: Thermo Fisher Scientific
Description: Titanium(IV) sulphide ≥99.8% (metals basis)

MSDS Certificates

Image Unavailable-B20063.0E

Thiram ≥97%

Supplier: Thermo Fisher Scientific
Description: Thiram ≥97%

MSDS Certificates

Image Unavailable-APOSBIT0122-5G

TCEP-HCl (Tris(2-carboxyethyl)phosphine hydrochloride) 98%

Supplier: Apollo Scientific
Description: Used in the reduction of disulphide groups.

Product Image-ACRO210891000

Lawesson's reagent 99%

Supplier: Thermo Fisher Scientific
Description: CAS No.: 19172-47-5

MSDS

Image Unavailable-A14530.14

Lawesson's reagent 97%

Supplier: Thermo Fisher Scientific
Description: Lawesson's reagent 97%

MSDS Certificates

Image Unavailable-CAYM14882-500

Cystamine dihydrochloride ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Cystamine is an organic disulfide that inhibits TGM2 with an IC50 value of approximately 2.5 mM.

Product Image-ACRO111771000

Cystamine dihydrochloride 97%

Supplier: Thermo Fisher Scientific
Description: Cystamine dihydrochloride 97%

MSDS

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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