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Image Unavailable-BOSSBS-1970R-A750

Anti-LAMP-1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1970R-A750)
Supplier: Bioss
Description: Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localisation of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
UOM: 1 * 100 µl
Image Unavailable-LEIM31154202

Microsystems™ Schott Gooseneck Light Guide

Catalog Number: (LEIM31154202)
Supplier: LEICA MICROSYSTEMS
Description: High quality schott fiber optics for perfect light placement. Microsystems™ Schott Gooseneck Light Guide provides flex and stay lighting.
UOM: 1 * 1 items

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Product Image-SCTV108336-T

SymLine Automatic Switching for Container

Supplier: S.C.A.T.
Description: The ready-to-use automatic switching sets prevent the overflowing of disposal containers and the associated leakage of hazardous, toxic, or explosive liquid waste.

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Product Image-630-1528

LED cold light source, KL 300 LED (without fan)

Catalog Number: (630-1528)
Supplier: SCHOTT AG Lighting and imaging
Description: This compact LED cold light source for eco-friendly PURAVIS® light guides is driven by a single LED and provides a brightness equivalent to a 30 W halogen lamp and is therefore ideal as a standard illumination system for the requirements of routine inspections and education.
UOM: 1 * 1 items
Product Image-SCOC157406

Ring lights for KL series

Supplier: SCHOTT AG Lighting and imaging
Description: Ring lights are used to provide intense, uniform and shadow-free illumination.

Image Unavailable-BOSSBS-2702R-CY7

Anti-SEMA7A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2702R-CY7)
Supplier: Bioss
Description: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
UOM: 1 * 100 µl
Product Image-630-1196

Ring light, VisiLED Darkfield

Catalog Number: (630-1196)
Supplier: SCHOTT AG Lighting and imaging
Description: VisiLED Darkfield ring light provides intensive illumination in the incident darkfield, enhancing contrasts of flat structured surfaces.
UOM: 1 * 1 items
Image Unavailable-WLDM113714000-0080

TEVISIO, TVD 750/940/DM Magnifier Luminaire

Catalog Number: (WLDM113714000-0080)
Supplier: WALDMANN
Description: The TEVISIO magnifier luminaire delivers delight right across the range. Either in terms of fast and problem-free lens changes, the flexible lens ring with bayonet connection, or the perfectly conceived technical lighting concept or the visualiser function that suddenly also makes unseen errors visible.
UOM: 1 * 1 items
Product Image-634-0600

VWR® Hitachi F-2700, Fluorescence spectrophotometer

Catalog Number: (634-0600)
Supplier: VWR Collection
Description: Flexible instrument with excellent performance and range of functionality.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-11751R-CY7

Anti-PQBP1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11751R-CY7)
Supplier: Bioss
Description: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11751R-A488

Anti-PQBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-11751R-A488)
Supplier: Bioss
Description: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11751R-A680

Anti-PQBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11751R-A680)
Supplier: Bioss
Description: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid Signalling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11072R

Anti-ASTN2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11072R)
Supplier: Bioss
Description: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11369R

Anti-SYNGAP Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11369R)
Supplier: Bioss
Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10392R

Anti-SYNGAP Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-10392R)
Supplier: Bioss
Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2702R-A680

Anti-Semaphorin 7A Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-2702R-A680)
Supplier: Bioss
Description: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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