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Image Unavailable-PRSI92-034

Human Recombinant Kidney-Type Arginase (from E. coli)

Catalog Number: (PRSI92-034)
Supplier: ProSci Inc.
Description: Kidney-Type Arginase (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyses the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase.
UOM: 1 * 50 µG
Image Unavailable-PRSI33-182

Anti-ODC1 Mouse Monoclonal Antibody [clone: ODC1/485]

Catalog Number: (PRSI33-182)
Supplier: ProSci Inc.
Description: This antibody recognises a 53 kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
UOM: 1 * 100 µG

New Product


Image Unavailable-PRSI33-884

Anti-ODC1 Mouse Monoclonal Antibody [clone: ORN255-1]

Catalog Number: (PRSI33-884)
Supplier: ProSci Inc.
Description: Ornithine Decarboxylase (ODC) is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyses ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [RefSeq].
UOM: 1 * 100 µG

New Product


Product Image-PRSI29-641

Anti-OTC Rabbit Polyclonal Antibody

Catalog Number: (PRSI29-641)
Supplier: ProSci Inc.
Description: OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
UOM: 1 * 100 µG
Product Image-00221.

Nitric oxide reagents and kits

Supplier: Biotium
Description: Nitric oxide donors, nitric oxide synthase inhibitors and nitric oxide detection reagents and kits for nitric oxide (NO) studies.

Image Unavailable-BSBTA00721-1

Anti-OTC Rabbit Polyclonal Antibody

Catalog Number: (BSBTA00721-1)
Supplier: Boster Bio
Description: Rabbit IgG polyclonal antibody for Ornithine carbamoyltransferase, mitochondrial(OTC) detection. Tested with WB in Human;Mouse;Rat.
UOM: 1 * 100 µG
Product Image-PRSI29-912

Anti-SLC7A1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI29-912)
Supplier: ProSci Inc.
Description: SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.
UOM: 1 * 50 µG
Image Unavailable-PRSI33-424

Anti-ARG1 Mouse Monoclonal Antibody [clone: ARG1/1126]

Catalog Number: (PRSI33-424)
Supplier: ProSci Inc.
Description: This protein is involved in the pathway that synthesizes L-ornithine and urea from L-arginine.
UOM: 1 * 100 µG

New Product


Image Unavailable-PRSI33-451

Anti-ODC1 Mouse Monoclonal Antibody [clone: ODC1/487]

Catalog Number: (PRSI33-451)
Supplier: ProSci Inc.
Description: Recognises a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
UOM: 1 * 100 µG

New Product


Image Unavailable-PRSI34-148

Anti-ODC1 Mouse Monoclonal Antibody [clone: SPM565]

Catalog Number: (PRSI34-148)
Supplier: ProSci Inc.
Description: Recognises a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
UOM: 1 * 100 µG

New Product


Product Image-PRSI26-283

Anti-OAT Rabbit Polyclonal Antibody

Catalog Number: (PRSI26-283)
Supplier: ProSci Inc.
Description: OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 50 µG
Image Unavailable-PRSI33-951

Anti-ARG1 Mouse Monoclonal Antibody [clone: T1ARG-1]

Catalog Number: (PRSI33-951)
Supplier: ProSci Inc.
Description: Arginase catalyses the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterised by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [RefSeq].
UOM: 1 * 100 µG

New Product


Image Unavailable-J60890.MF

Nω-Methyl-L-arginine monoacetate ≥99%

Catalog Number: (J60890.MF)
Supplier: Thermo Fisher Scientific
Description: Nω-Methyl-L-arginine monoacetate ≥99%
UOM: 1 * 50 mg

MSDS Certificates


Product Image-PRSI96-034

Human recombinant Arginase 1 (from HEK293 cells)

Catalog Number: (PRSI96-034)
Supplier: ProSci Inc.
Description: Arginase-1 (ARG1) is also known as Liver-type arginase, Type I arginase, which belongs to the arginase family. Arginase-1 / ARG1 is a manganese-containing enzyme. The reaction catalysed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. Defects in Arginase-1 / ARG1 are the cause of argininemia (ARGIN).
UOM: 1 * 50 µG
Image Unavailable-PRSI91-585

Human recombinant GFER (from E. coli)

Catalog Number: (PRSI91-585)
Supplier: ProSci Inc.
Description: GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration. GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC). S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines.
UOM: 1 * 50 µG
Product Image-PRSI25-230

Anti-CNBP Rabbit Polyclonal Antibody

Catalog Number: (PRSI25-230)
Supplier: ProSci Inc.
Description: CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 50 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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