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Image Unavailable-20368-500UL

Anti-IgG Goat Polyclonal Antibody (CF™ 660C)

Catalog Number: (20368-500UL)
Supplier: Biotium
Description: CF™660C and CF™660R antibodies are affinity-purified antibodies labeled with far-red fluorescent CF™660C or CF™660R dyes, members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,5 mL
Image Unavailable-BOSSBS-11703R-A680

Anti-FMR2/AFF2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11703R-A680)
Supplier: Bioss
Description: FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.
UOM: 1 * 100 µl
Product Image-521-2657

VWR® Micro Star 21/21R Microcentrifuges, Ventilated/Refrigerated

Supplier: VWR Collection
Description: Micro Star 21 and 21R microcentrifuges combine power, versatility and convenience in a safe, compact, easy to use laboratory instrument. Both the ventilated Micro Star 21 and the refrigerated Micro Star 21R are excellent choice for routine sample preparation process and for high-end research applications. The special biocontainment rotor lid, for one-click rotor opening and closing, shortens retrieval time compared to screw on lids.

Environmentally Preferable

Image Unavailable-BOSSBS-2130R-CY7

Anti-MKI67 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-2130R-CY7)
Supplier: Bioss
Description: Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2130R-A555

Anti-MKI67 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-2130R-A555)
Supplier: Bioss
Description: Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLEI3050010

1,9-Pyrazoloanthrone ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent, cell permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50=40nM for JNK-1 and JNK-2 and 90nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold greater selectivity for JNK as compared to ERK1 and p38. Inhibits the phosphorylation of c-Jun and blocks the expression of IL-2, IFN-γ, TNF-α, and COX-2. Blocks IL-1-induced accumulation of phospho-Jun, induction of c-Jun transcription and anti CD3-induced apoptosis of CD4+ CD8+ thymocytes.

Image Unavailable-BOSSBS-9717R-A750

Anti-Nidogen 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-9717R-A750)
Supplier: Bioss
Description: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9717R

Anti-Nidogen 2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-9717R)
Supplier: Bioss
Description: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl
Image Unavailable-20379-50UL

Anti-IgG Goat Polyclonal Antibody (CF™ 790)

Catalog Number: (20379-50UL)
Supplier: Biotium
Description: Near-infrared CF™ dye antibodies are affinity-purified antibodies labeled with near-infrared fluorescent CF™750 or CF™770, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 50 µl
Image Unavailable-20378-50UL

Anti-IgG Goat Polyclonal Antibody (CF™ 790)

Catalog Number: (20378-50UL)
Supplier: Biotium
Description: Near-infrared CF™ dye antibodies are affinity-purified antibodies labeled with near-infrared fluorescent CF™750 or CF™770, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 50 µl
Image Unavailable-BOSSBS-8254R-A488

Anti-DENND1B Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-8254R-A488)
Supplier: Bioss
Description: Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes.Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7696R-A647

Anti-CSRNP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-7696R-A647)
Supplier: Bioss
Description: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7696R-A555

Anti-CSRNP1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-7696R-A555)
Supplier: Bioss
Description: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-L0138-500

Cell culture media, Ham's F14 (F-14 Nutrient Medium)

Catalog Number: (L0138-500)
Supplier: Biowest
Description: Ham's F14 medium was developed from Ham's F12 medium, which was originally developed for the serum-free clonal growth of Chinese Hamster Ovary (CHO) cells, lung cells and mouse L-cells. Ham's F14 contains a double concentration of amino acids compared to the Ham's F12 medium. This product is also supplemented with calcium chloride and ascorbic acid.
UOM: 1 * 500 mL

Certificates


Image Unavailable-BOSSBS-15483R-CY5

Anti-HIBADH Rabbit Polyclonal Antibody (Cy5)

Catalog Number: (BOSSBS-15483R-CY5)
Supplier: Bioss
Description: HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
UOM: 1 * 100 µl
Product Image-IMMRIR1408

Anti-IgY Goat Polyclonal Antibody (DyLight® 633)

Catalog Number: (IMMRIR1408)
Supplier: ImmunoReagents
Description: The ImmunoReagents' DyLight® 633 conjugates fluoresces red with physical properties comparable to other 633 dyes. DyLight® 633 is ideal for multi-Colour applications. DyLight® 633 is available as reactive labeling agents and as conjugates of secondary antibodies and biotin-binding proteins for use in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 638nm/658nm Emission Colour = Red (Similar Dyes: Alexa Fluor 633).
UOM: 1 * 1 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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