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Image Unavailable-BOSSBS-5046R-A555

Anti-CYP46A1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-5046R-A555)
Supplier: Bioss
Description: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Product Image-BOSSBS-7544R

Anti-SOAT1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7544R)
Supplier: Bioss
Description: Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.
UOM: 1 * 100 µl

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Image Unavailable-CAYM10009779-192

Cholesterol cell-based detection assay kit

Catalog Number: (CAYM10009779-192)
Supplier: Cayman Chemical
Description: Cholesterol Cell-Based Detection Assay Kit is a 192-well assay for measurement of cholesterol.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-8672R

Anti-HDLBP Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-8672R)
Supplier: Bioss
Description: HDL is a cholesterol carrier protein that acts as scavenger of tissue cholesterol. It is important in cholesterol efflux from tissues, and involved in the return of cholesterol from the periphery to the liver for removal as bile acids.This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Product Image-ABCAAB285294-96

QuickDetect™ Free Cholesterol (fCHOL) (Mouse) ELISA Kit

Catalog Number: (ABCAAB285294-96)
Supplier: Abcam
Description: A rapid sandwich ELISA kit to quantify fCHOL in mouse serum, plasma, cell culture supernatnat.
UOM: 1 * 96 Tests
Image Unavailable-BOSSBS-12324R-CY7

Anti-PTCHD2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-12324R-CY7)
Supplier: Bioss
Description: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12324R-CY5

Anti-PTCHD2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-12324R-CY5)
Supplier: Bioss
Description: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3694R-CY5.5

Anti-CETP Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-3694R-CY5.5)
Supplier: Bioss
Description: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
UOM: 1 * 100 µl
Product Image-ABCAAB285242-96

QuickDetect™ Total Cholesterol (Mouse) ELISA Kit

Catalog Number: (ABCAAB285242-96)
Supplier: Abcam
Description: Rapid sandwich ELISA kit to quantify Total cholesterol in mouse serum, plasma, culture supernatnat.
UOM: 1 * 96 Tests
Image Unavailable-BOSSBS-3694R-A555

Anti-CETP Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-3694R-A555)
Supplier: Bioss
Description: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12324R-A750

Anti-PTCHD2/DISP3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12324R-A750)
Supplier: Bioss
Description: PTCHD2 is a 1392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6764R

Anti-NPC1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-6764R)
Supplier: Bioss
Description: This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5051R

Anti-CYP46 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5051R)
Supplier: Bioss
Description: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5046R-CY5.5

Anti-CYP46A1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5046R-CY5.5)
Supplier: Bioss
Description: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-USBIC5045-35

Anti-Cholesterol Acyltransferase 1 Rabbit Polyclonal Antibody

Catalog Number: (USBIC5045-35)
Supplier: US Biological
Description: Anti-Cholesterol Acyltransferase 1 Rabbit Polyclonal Antibody
UOM: 1 * 1 Vial
Image Unavailable-BOSSBS-5046R-CY3

Anti-CYP46A1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5046R-CY3)
Supplier: Bioss
Description: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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