Print…

You Searched For: CPC+COLDER


460  results were found

Refine Results Sort by
SearchResultCount:"460"

Sort Results

List View Easy View

Rate These Search Results

Image Unavailable-BOSSBS-0615R-A488

Anti-BIRC5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-0615R-A488)
Supplier: Bioss
Description: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Isoform 2 and isoform 3 do not appear to play vital roles in mitosis. Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8048R

Anti-KLHL21 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-8048R)
Supplier: Bioss
Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8048R-A647

Anti-KLHL21 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-8048R-A647)
Supplier: Bioss
Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
UOM: 1 * 100 µl
Product Image-PRSI80-031

Anti-AURKB Rabbit Polyclonal Antibody

Catalog Number: (PRSI80-031)
Supplier: ProSci Inc.
Description: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity.
UOM: 1 * 100 µG
Image Unavailable-PRSI92-047

Human recombinant BIRC5 (from E. coli)

Catalog Number: (PRSI92-047)
Supplier: ProSci Inc.
Description: Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
UOM: 1 * 50 µG
Product Image-PRSI32-114

Anti-AURKB Mouse Monoclonal Antibody

Catalog Number: (PRSI32-114)
Supplier: ProSci Inc.
Description: AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases
UOM: 1 * 100 µl
Product Image-KWIN110149941S

Winter jacket, Acode® Summit Winter

Supplier: FRISTADS KANSAS
Description: Wind- and waterproof polyester jackets with soft outer fabric and taped seams. Ideal for outdoor use on colder days. The jackets for women have a tailored fit.

Product Image-PRSI4751

Anti-CDCA8 Rabbit Polyclonal Antibody

Catalog Number: (PRSI4751)
Supplier: ProSci Inc.
Description: CDCA8 Antibody: CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division. It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase. CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues. In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation. Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53. Its aberrant expression is linked to a poor prognosis for gastric cancer.
UOM: 1 * 100 µG
Product Image-A7153.2500RF

Decontamination solution, RNase-ExitusPlus™

Supplier: PanReac AppliChem
Description: RNase-ExitusPlus™ is a non-alkaline, non-corrosive and non-carcinogenic cleansing solution that is highly active against RNase contamination. RNase-ExitusPlus™ has been demonstrated to inactivate more than 20 μg of RNase A dried onto the bottom of a microcentrifuge tube. RNase-ExitusPlus™ is stable for approximately 18 months and heat resistant. It should be stored at room temperature; at colder temperatures a precipitate may form which is easily brought into solution at 37 °C. RNase-ExitusPlus™ is supplied in spray bottles and a one litre refill pack is also available.

MSDS Certificates

Image Unavailable-MFLX00264-RF

CPC (Colder) Drum Buttress Adptr 2'' W/Viton Seal 25/Pk 1 * 25 items

Catalog Number: (MFLX00264-RF)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) Drum Buttress Adptr 2'' W/Viton Seal 25/Pk 1 * 25 items
UOM: 1 * 25 items
Image Unavailable-MFLX49009-35

CPC (Colder) Drum Adapter Kit 1 * 1 items

Catalog Number: (MFLX49009-35)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) Drum Adapter Kit 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-MFLA06360-92

CPC (Colder) Quick-Disconnect Fitting, Hosebarb Insert, Acetal, Straight-Through, 1/4 INCH ID 1 * 5 items

Catalog Number: (MFLA06360-92)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) Quick-Disconnect Fitting, Hosebarb Insert, Acetal, Straight-Through, 1/4 INCH ID 1 * 5 items
UOM: 1 * 5 items
Image Unavailable-MFLX00137-OB

CPC (Colder) 3/8 Hose Barb Non Valve Insert 250 Pkg 1 * 250 items

Catalog Number: (MFLX00137-OB)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) 3/8 Hose Barb Non Valve Insert 250 Pkg 1 * 250 items
UOM: 1 * 250 items
Image Unavailable-MFLX61129-38

CPC (Colder) Mpc Body X Mpc Back-To-Back Body Adapter Mpc17C1703 Min 25 1 * 1 items

Catalog Number: (MFLX61129-38)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) Mpc Body X Mpc Back-To-Back Body Adapter Mpc17C1703 Min 25 1 * 1 items
UOM: 1 * 1 items

Certificates


Image Unavailable-MFLX00245-PN

CPC (Colder) COUPLING 1/4 INCH ID ELBOW EA 1 * 1 items

Catalog Number: (MFLX00245-PN)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) COUPLING 1/4 INCH ID ELBOW EA 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-MFLX78001-73

CPC (Colder) Fittings PC 3/8 INCH 1 * 250 items

Catalog Number: (MFLX78001-73)
Supplier: Avantor Fluid Handling
Description: CPC (Colder) Fittings PC 3/8 INCH 1 * 250 items
UOM: 1 * 250 items
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
177 - 192 of 460
no targeter for Bottom