You Searched For: CENTA\u2122+\u03B2-Lactamase+Substrate

Catalog Number: (BOSSBS-6056R-FITC)

Supplier: Bioss

Description: Hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues

UOM: 1 * 100 µl

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Supplier: Apollo Scientific

Description: Chromogenic substrate for b-Galactosidase. Reported to produce a deeper blue water insoluble colouration than X-Gal.

Catalog Number: (BOSSBS-8363R-CY5)

Supplier: Bioss

Description: The regulated oscillation of protein expression is an essential mechanism of cell cycle control. The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core. NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry. Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, which restricts substrate ubiquitination activity to interphase. Nuclear cyclin B1 is a substrate of SCFNIPA. Inactivation of NIPA by RNAi results in nuclear accumulation of cyclin B1 in interphase, activation of cyclin B1-Cdk1 kinase activity, and premature mitotic entry. Thus, SCFNIPA-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-8363R-A555)

Supplier: Bioss

Description: The regulated oscillation of protein expression is an essential mechanism of cell cycle control. The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core. NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry. Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, which restricts substrate ubiquitination activity to interphase. Nuclear cyclin B1 is a substrate of SCFNIPA. Inactivation of NIPA by RNAi results in nuclear accumulation of cyclin B1 in interphase, activation of cyclin B1-Cdk1 kinase activity, and premature mitotic entry. Thus, SCFNIPA-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-8363R-FITC)

Supplier: Bioss

Description: The regulated oscillation of protein expression is an essential mechanism of cell cycle control. The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core. NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry. Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, which restricts substrate ubiquitination activity to interphase. Nuclear cyclin B1 is a substrate of SCFNIPA. Inactivation of NIPA by RNAi results in nuclear accumulation of cyclin B1 in interphase, activation of cyclin B1-Cdk1 kinase activity, and premature mitotic entry. Thus, SCFNIPA-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5799R-CY3)

Supplier: Bioss

Description: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-12574R-FITC)

Supplier: Bioss

Description: p130 represents one of several known substrates for v-Crk encoded p47. p130 Cas (for Crk-associated substrate) exhibits a high level of tyrosine phosphorylation and is tightly associated with v-Crk, suggesting a role in v-Crk-mediated cell signaling. The molecular cloning of p130 Cas has shown it to represent a novel SH3 containing signaling molecule with a cluster of multiple putative SH2-binding motifs for v-Crk. By immunoprecipitation analysis, p130 Cas has been shown to be highly phosphorylated at tyrosine residues subsequent to either v-Src p60 or v-Crk-mediated transformation and to form stable complexes with both of these transforming proteins. p130 Cas behaves as an extremely potent substrate for protein tyrosine kinases and has been reported to relocate from the cytoplasm to cell membrane upon tyrosine phosphorylation. One proposed model is that the SH2 domain of v-Crk functions to activate c-Src kinase, which in turn phosphorylates p130 Cas.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-12574R-A647)

Supplier: Bioss

Description: p130 represents one of several known substrates for v-Crk encoded p47. p130 Cas (for Crk-associated substrate) exhibits a high level of tyrosine phosphorylation and is tightly associated with v-Crk, suggesting a role in v-Crk-mediated cell signaling. The molecular cloning of p130 Cas has shown it to represent a novel SH3 containing signaling molecule with a cluster of multiple putative SH2-binding motifs for v-Crk. By immunoprecipitation analysis, p130 Cas has been shown to be highly phosphorylated at tyrosine residues subsequent to either v-Src p60 or v-Crk-mediated transformation and to form stable complexes with both of these transforming proteins. p130 Cas behaves as an extremely potent substrate for protein tyrosine kinases and has been reported to relocate from the cytoplasm to cell membrane upon tyrosine phosphorylation. One proposed model is that the SH2 domain of v-Crk functions to activate c-Src kinase, which in turn phosphorylates p130 Cas.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-0987R-CY5)

Supplier: Bioss

Description: Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

UOM: 1 * 100 µl

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Catalog Number: (ENZOBMLAK4140001)

Supplier: ENZO LIFE SCIENCES

Description: A QuantiZyme™ Assay System. The MMP-8 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-8 (MMP-8, neutrophil collagenase, collagenase-2) using a thiopeptide as a chromogenic substrate.

UOM: 1 * 1 KIT

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Catalog Number: (BOSSBS-10383R)

Supplier: Bioss

Description: The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Catalog Number: (IMMRIR1745)

Supplier: ImmunoReagents

Description: ImmunoReagents Alkaline Phosphatase (AP) antibody conjugates are used in ELISA, Immunohistochemistry (IHC) and Western blotting techniques. AP is a 140 kDa enzyme that changes color in the presence of PNPP or BCIP/NBT substrates. These conjugates have a linear reaction rate thus allowing the researcher to increase sensitivity by prolonging substrate incubation times.

UOM: 1 * 0,5 mg

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Catalog Number: (IMMRIR1358)

Supplier: ImmunoReagents

Description: ImmunoReagents’ Alkaline Phosphatase (AP) antibody conjugates are used in ELISA, Immunohistochemistry (IHC) and Western blotting techniques. AP is a 140 kDa enzyme that changes Colour in the presence of PNPP or BCIP/NBT substrates. These conjugates have a linear reaction rate thus allowing the researcher to increase sensitivity by prolonging substrate incubation times.

UOM: 1 * 1 mg

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Catalog Number: (BOSSBS-5148R-CY7)

Supplier: Bioss

Description: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5148R-CY5)

Supplier: Bioss

Description: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.

UOM: 1 * 100 µl

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Catalog Number: (1303750.)

Supplier: USP

Description: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

UOM: 1 * 100 g

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