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You Searched For: CENTA\u2122+\u03B2-Lactamase+Substrate


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Product Image-ENZOBMLP1320500

TACE substrate (fluorogenic)

Catalog Number: (ENZOBMLP1320500)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
UOM: 1 * 0,5 mg
Image Unavailable-ENZOBMLP1910001

Crosstide

Catalog Number: (ENZOBMLP1910001)
Supplier: ENZO LIFE SCIENCES
Description: Akt substrate
UOM: 1 * 1 mg
Image Unavailable-ENZOALX260082M005

Ac-WEHD-pNA ≥98% (by HPLC)

Catalog Number: (ENZOALX260082M005)
Supplier: ENZO LIFE SCIENCES
Description: Colorimetric caspase substrate for caspase-1, -4, -5 and -14.
UOM: 1 * 5 mg
Image Unavailable-ENZOALX155023M001

Human EGF receptor (652-657)

Catalog Number: (ENZOALX155023M001)
Supplier: ENZO LIFE SCIENCES
Description: Specific PKC substrate
UOM: 1 * 1 mg
Image Unavailable-41434.KT

Aluminium lanthanum (III) oxide substrate 10x10x0.5 mm, polished both sides 100 orientation

Catalog Number: (41434.KT)
Supplier: Thermo Fisher Scientific
Description: Aluminium lanthanum (III) oxide substrate 10x10x0.5 mm, polished both sides 100 orientation
UOM: 1 * 1 items

MSDS Certificates


Image Unavailable-30015.

3,3'-Diaminobenzidine tetrahydrochloride (DAB HCl) kit peroxidase substrate

Catalog Number: (30015.)
Supplier: Biotium
Description: DAB (3,3′-diaminobenzidine) reacts with HRP in the presence of peroxide to yield an insoluble brown-colored product at locations where peroxidase-conjugated antibodies are bound to samples. The brown precipitate is insoluble in alcohol and other organic solvents, making it an excellent substrate for immunohistochemical staining that requires the use of traditional counterstains and mounting media.
UOM: 1 * 1 KIT
Image Unavailable-ENZOALX260044M005

Z-IETD-pNA

Catalog Number: (ENZOALX260044M005)
Supplier: ENZO LIFE SCIENCES
Description: Caspase and granzyme substrate
UOM: 1 * 5 mg
Product Image-ENZOBMLST5020010

7-HC-arachidonate ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Phospholipase substrate.

Image Unavailable-BOSSBS-1135R-HRP

Anti-SRC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-1135R-HRP)
Supplier: Bioss
Description: c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1135R-A555

Anti-SRC Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1135R-A555)
Supplier: Bioss
Description: c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
UOM: 1 * 100 µl
Image Unavailable-38509.KT

Single crystal substrates

Supplier: Thermo Fisher Scientific
Description: A single crystal is a material in which the crystal lattice of the entire sample is continuous and unbroken to the edges of the sample, with no grain boundaries.

MSDS Certificates

Image Unavailable-ENZOBMLP4500005

WP-AMC

Catalog Number: (ENZOBMLP4500005)
Supplier: ENZO LIFE SCIENCES
Description: DPP substrate
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLP1990010

Z-VVR-AMC

Catalog Number: (ENZOBMLP1990010)
Supplier: ENZO LIFE SCIENCES
Description: Substrate for cathepsin S and cathepsin L
UOM: 1 * 10 mg
Image Unavailable-ENZOALX260050M005

BAADT

Catalog Number: (ENZOALX260050M005)
Supplier: ENZO LIFE SCIENCES
Description: Granzyme B substrate
UOM: 1 * 5 mg
Image Unavailable-53877-100MG

Organic reference standard, 2,6-Dimethoxyphenol, analytical standard, Supelco®

Catalog Number: (53877-100MG)
Supplier: Merck
Description: 2,6-Dimethoxyphenol can find applications mainly as a substrate of laccases catalysis and also determine its activity in aqueous solution. It can also be used as a potential marker compound for emission of smoke in the atmosphere from wood.
UOM: 1 * 100 mg
Image Unavailable-ENZOBMLSE2110025

Ubiquitin-AMC

Catalog Number: (ENZOBMLSE2110025)
Supplier: ENZO LIFE SCIENCES
Description: High purity industry standard substrate for deubiquitinylating enzymes (DUBs).
UOM: 1 * 25 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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