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Catalog Number: (ENZOBMLP1070001)
Supplier: ENZO LIFE SCIENCES
Description: PKA substrate
UOM: 1 * 1 mg


Supplier: ENZO LIFE SCIENCES
Description: Caspase-6 substrate

Catalog Number: (ENZOBMLP1890005)
Supplier: ENZO LIFE SCIENCES
Description: DPP substrate
UOM: 1 * 5 mg


Catalog Number: (BOSSBS-1135R-CY5)
Supplier: Bioss
Description: c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
UOM: 1 * 100 µl


Supplier: ENZO LIFE SCIENCES
Description: Caspase-9 substrate

Catalog Number: (USBIR1200-13A)
Supplier: US Biological
Description: Anti-Ras-related C3 Botulinum Toxin Substrate 1, Isoform Rac1 Chicken Polyclonal Antibody
UOM: 1 * 50 µG


Supplier: G-Biosciences
Description: A ready to use modified TMB (3, 3’, 5, 5’-Tetramethylbenzidine) substrate is used that generates a dark blue precipitate in the presence of horseradish peroxidase.

Catalog Number: (BOSSBS-4210R-CY7)
Supplier: Bioss
Description: Hydrolyzes acyl-CoA thioesters (in vitro). Has a preference for substrates with medium chain length (C1-C14). Inactive towards substrates with C18 or C2 aliphatic chains. Its physiological substrate is not known.
UOM: 1 * 100 µl


Supplier: ENZO LIFE SCIENCES
Description: Caspase-3 substrate

Catalog Number: (ENZOBMLP2390001)
Supplier: ENZO LIFE SCIENCES
Description: Pyruvate kinase substrate
UOM: 1 * 1 mg


Catalog Number: (ENZOALX260078M005)
Supplier: ENZO LIFE SCIENCES
Description: Caspase-3 substrate
UOM: 1 * 5 mg


Catalog Number: (ENZOALX260050M005)
Supplier: ENZO LIFE SCIENCES
Description: Granzyme B substrate
UOM: 1 * 5 mg


Supplier: ENZO LIFE SCIENCES
Description: Caspase substrate

Catalog Number: (ENZOBMLP2480001)
Supplier: ENZO LIFE SCIENCES
Description: Protein kinase substrate
UOM: 1 * 1 mg


Catalog Number: (215643-5G)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Disperse blue 1 is a grey to black powder. Disperse dyes are known to be insoluble in water and are applied to the substrate as suspensions or dispersions by dissolving in hydrophobic regions of the polymers making up the fiber.
UOM: 1 * 5 g


Catalog Number: (ENZOALX260023M001)
Supplier: ENZO LIFE SCIENCES
Description: Substrate for caspase-1 and -4
UOM: 1 * 1 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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