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Catalog Number: (ENZOBMLP2510100)
Supplier: ENZO LIFE SCIENCES
Description: Protein kinase substrate
UOM: 1 * 100 µG


Catalog Number: (ENZOBMLP2490001)
Supplier: ENZO LIFE SCIENCES
Description: Protein kinase substrate
UOM: 1 * 1 mg


Catalog Number: (ENZOALX260049M001)
Supplier: ENZO LIFE SCIENCES
Description: Caspase-1 substrate
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP1420020)
Supplier: ENZO LIFE SCIENCES
Description: Cathepsin K substrate
UOM: 1 * 20 mg


Supplier: G-Biosciences
Description: The femtoELISA™ kits utilise a non animal protein blocker, NAP-BLOCKER™ that minimises cross-reactivity with researcher's antigens and antibodies. For the detection of HRP, an improved, ultra sensitive, non volatile, stable colorimetric substrate based on tetramethyl benzidine (TMB) is supplied. Reagent does not require hydrogen peroxide that can have detrimental effects on many biological factors, which may ultimately affect the assays.
Catalog Number: (BOSSBS-1135R-CY5)
Supplier: Bioss
Description: c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
UOM: 1 * 100 µl


Catalog Number: (ENZOBMLP3150500)
Supplier: ENZO LIFE SCIENCES
Description: Insulin receptor substrate
UOM: 1 * 0,5 mg


Catalog Number: (ENZOBMLP2570001)
Supplier: ENZO LIFE SCIENCES
Description: Protein kinase substrate
UOM: 1 * 1 mg


Catalog Number: (BOSSBS-4210R-A680)
Supplier: Bioss
Description: hydrolyses acyl-CoA thioesters (in vitro). Has a preference for substrates with medium chain length (C1-C14). Inactive towards substrates with C18 or C2 aliphatic chains. Its physiological substrate is not known.
UOM: 1 * 100 µl


Supplier: Merck
Description: Immobilon® Western HRP substrates are compatible with both PVDF and nitrocellulose membranes, as well as all commonly used buffers and blocking reagents.

Catalog Number: (APOSBIM1206-5G)
Supplier: Apollo Scientific
Description: Substrate for b-D-Glucosidase
UOM: 1 * 5 g


Supplier: Apollo Scientific
Description: Substrate for CYP2B6.

Supplier: ENZO LIFE SCIENCES
Description: Substrate for caspase-1 and -4

Supplier: ENZO LIFE SCIENCES
Description: Caspase-8 substrate

Supplier: ENZO LIFE SCIENCES
Description: Caspase-1 substrate

Supplier: Apollo Scientific
Description: Fluorescent substrate for a-D-mannosidase.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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