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Image Unavailable-BOSSBS-1657R-A647

Anti-STAT1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1657R-A647)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10756R-A488

Anti-MTP18 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-10756R-A488)
Supplier: Bioss
Description: MTP18 (Mitochondrial protein 18 kDa) is a downstream target of the phosphatidylinositol 3-kinase signaling pathway and is essential for cell viability. It may have a role in maintaining the integrity of the mitochondrial network. Loss of function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-10756R-A647

Anti-MTP18 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-10756R-A647)
Supplier: Bioss
Description: MTP18 (Mitochondrial protein 18 kDa) is a downstream target of the phosphatidylinositol 3-kinase signaling pathway and is essential for cell viability. It may have a role in maintaining the integrity of the mitochondrial network. Loss of function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-CY5.5

Anti-STAT1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1657R-CY5.5)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3265R-A750

Anti-Mcl1 Ser159 + Thr163 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-3265R-A750)
Supplier: Bioss
Description: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10756R-CY5

Anti-MTP18 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-10756R-CY5)
Supplier: Bioss
Description: MTP18 (Mitochondrial protein 18 kDa) is a downstream target of the phosphatidylinositol 3-kinase signaling pathway and is essential for cell viability. It may have a role in maintaining the integrity of the mitochondrial network. Loss of function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13928R-A750

Anti-CHPF Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-13928R-A750)
Supplier: Bioss
Description: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4009R-A555

Anti-ATG4D Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-4009R-A555)
Supplier: Bioss
Description: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-A680

Anti-STAT1 Tyr701 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-1657R-A680)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-A555

Anti-STAT1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1657R-A555)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-CY5

Anti-STAT1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1657R-CY5)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-CY7

Anti-STAT1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1657R-CY7)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5194R

Anti-AKT1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5194R)
Supplier: Bioss
Description: AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5188R

Anti-AKT1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5188R)
Supplier: Bioss
Description: AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-A750

Anti-STAT1 Tyr701 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1657R-A750)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1657R-FITC

Anti-STAT1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1657R-FITC)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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