You Searched For: 8-Phenyl-1,4-dioxaspiro[4.5]decane-8-carbaldehyde


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Supplier: Apollo Scientific
Description: 8-Phenyl-1,4-dioxaspiro[4.5]decane-8-carbaldehyde

Supplier: ENZO LIFE SCIENCES AG
Description: Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.

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Supplier: Cayman Chemical
Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC<sub>50</sub> = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.

Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decane-8-methanol

New Product

Catalog Number: (APOSOR451151-1G)
Supplier: Apollo Scientific
Description: 8-(Iodomethyl)-1,4-dioxaspiro[4.5]decane
UOM: 1 * 1 g


Catalog Number: (APOSOR451152-1G)
Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decane-8-carboxaldehyde
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: 8-(Bromomethyl)-1,4-dioxaspiro[4.5]decane

Catalog Number: (APOSOR451153-5G)
Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decane-8-acetic acid
UOM: 1 * 5 g


Supplier: Apollo Scientific
Description: (R)-1,4-Dioxaspiro[4.5]decane-2-carboxaldehyde 95%

Supplier: Thermo Scientific
Description: 1,4-Dioxaspiro[4.5]decan-8-one ≥97%
Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decane-8-carbonitrile 95%

Catalog Number: (H26037.03)
Supplier: Thermo Scientific
Description: 1,4-Dioxaspiro[4.5]decan-8-ol ≥90%
UOM: 1 * 1 g

Supplier: Apollo Scientific
Description: 8,8-Difluoro-1,4-dioxaspiro[4.5]decane

Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decane-8-carboxylic acid 95%

New Product

Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decan-8-one

Catalog Number: (APOSOR922251-1G)
Supplier: Apollo Scientific
Description: 1,4-Dioxaspiro[4.5]decan-7-one 95%
UOM: 1 * 1 g


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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