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You Searched For: 8-(4-Chlorophenylthio)guanosine+3\',5\'-cyclic+Monophosphothioate

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8-(4-Chlorophenylthio)guanosine+3\',5\'-cyclic+Monophosphothioate,+Rp-Isomer+triethylammonium+salt


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Image Unavailable-ENZOALX480032M001

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer triethylammonium salt ≥99% (by HPLC), high purity

Supplier: ENZO LIFE SCIENCES AG
Description: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

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Image Unavailable-ENZOBMLCN2060001

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer triethylammonium salt ≥98% (by HPLC)

Catalog Number: (ENZOBMLCN2060001)
Supplier: ENZO LIFE SCIENCES AG
Description: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS
UOM: 1 * 1 mg

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Image Unavailable-ENZOALX480072M001

Guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer sodium salt ≥98% (by HPLC)

Catalog Number: (ENZOALX480072M001)
Supplier: ENZO LIFE SCIENCES AG
Description: Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.
UOM: 1 * 1 mg

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Product Image-ENZOALX480088M005

8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate sodium salt ≥99% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG
Description: Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels.

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Image Unavailable-ENZOALX480031M005

8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate triethylammonium salt ≥99% (by HPLC)

Catalog Number: (ENZOALX480031M005)
Supplier: ENZO LIFE SCIENCES AG
Description: Activator of PKG and CNG channels.
UOM: 1 * 5 mg

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Image Unavailable-ENZOALX480024M001

8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Rp-Isomer sodium salt ≥99% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG
Description: Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

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Image Unavailable-ENZOALX480085M001

Adenosine-3’,5’-cyclic Monophosphothioate, Rp-Isomer sodium salt ≥99% (by HPLC)

Catalog Number: (ENZOALX480085M001)
Supplier: ENZO LIFE SCIENCES AG
Description: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).
UOM: 1 * 1 mg

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Product Image-ENZOALX480025M001

8-Bromoadenosine-3',5'-cyclic monophosphothioate, Sp-isomer sodium salt ≥98% (by HPLC)

Catalog Number: (ENZOALX480025M001)
Supplier: ENZO LIFE SCIENCES AG
Description: PKA activator.
UOM: 1 * 1 mg

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Product Image-ENZOALX480093M005

8-(4-Chlorophenylthio)-2'-O-methyladenosine-3’,5’-cyclic monophosphate sodium salt ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG
Description: Specific, potent and membrane permeant activator of the Epac cAMP receptor.

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Product Image-ENZOBMLCN1300100

8-(4-Chlorophenylthio)adenosine-3',5'-cyclic monophosphate sodium salt (synthetic) ≥96% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG
Description: PKA activator.

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Product Image-CAYM17966-100

3'3'-cGAMP (sodium salt) ≥98%

Supplier: Cayman Chemical
Description: 3'3'-cGAMP (sodium salt) ≥98%

Image Unavailable-BOSSBS-3892R-CY5

Anti-cGMP Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3892R-CY5)
Supplier: Bioss
Description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3892R-A680

Anti-cGMP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3892R-A680)
Supplier: Bioss
Description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13470R-CY5

Anti-GNGT1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-13470R-CY5)
Supplier: Bioss
Description: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13470R-A555

Anti-GNGT1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-13470R-A555)
Supplier: Bioss
Description: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13470R-A647

Anti-GNGT1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-13470R-A647)
Supplier: Bioss
Description: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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