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Description: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Catalog Number: BOSSBS-15581R-A750
UOM: 1 * 100 µl
Supplier: Bioss


Description: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Catalog Number: BOSSBS-15581R-A555
UOM: 1 * 100 µl
Supplier: Bioss


Description: Tubing set for vacuum and water connection, 12 m (6,25 m vacuum tube and 6,25 m water tube), For: Heidolph Hei-VAP
Catalog Number: HEID591-33000-01
UOM: 1 * 1 items
Supplier: Heidolph Instruments GmbH & Co.KG


Description: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Catalog Number: BOSSBS-3191R-A647
UOM: 1 * 100 µl
Supplier: Bioss


Description: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Catalog Number: BOSSBS-10246R
UOM: 1 * 100 µl
Supplier: Bioss


Description: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Catalog Number: BOSSBS-5735R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss


Description: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Catalog Number: BOSSBS-5735R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: This diaphragm pumps is double-head, dry-running devices used in a wide range of laboratory applications.
Catalog Number: KNFAN938.50KT.18
UOM: 1 * 1 items
Supplier: KNF


Description: <B>Hei-VAC Vario Tec </B>for Hei-VAP expert control / Hei-VAP ultimate control.
Catalog Number: HEID591-00171-00
UOM: 1 * 1 items
Supplier: Heidolph Instruments GmbH & Co.KG


Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
Catalog Number: BOSSBS-5517R-A680
UOM: 1 * 100 µl
Supplier: Bioss


Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
Catalog Number: BOSSBS-5517R-CY5
UOM: 1 * 100 µl
Supplier: Bioss


Description: Nalgene™ lab-grade, autoclavable clear tubing sets the standard for purity and quality, made from highest-grade resins, free from ortho-phthalate plasticisers.
Catalog Number: NALG8702-0210
UOM: 1 * 50 Feet
Supplier: Thermo Fisher Scientific

Environmentally Preferable


Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
Catalog Number: BOSSBS-5517R-FITC
UOM: 1 * 100 µl
Supplier: Bioss


Description: Glass flask, vacuum resistant
Catalog Number: SART6980232
UOM: 1 * 1 items
Supplier: Sartorius


Description: Series N 022 diaphragm pumps are single-head, dry-running devices used in a wide range of laboratory applications. They transfer, compress and pump down without contamination.
Catalog Number: 181-3212
UOM: 1 * 1 items
Supplier: KNF


Description: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
Catalog Number: BOSSBS-3407R
UOM: 1 * 100 µl
Supplier: Bioss


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