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Image Unavailable-BOSSBS-3568R-A488

Anti-SMC1A Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-3568R-A488)
Supplier: Bioss
Description: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12355R-FITC

Anti-ASPSCR1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-12355R-FITC)
Supplier: Bioss
Description: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4284R-CY3

Anti-RAD21 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-4284R-CY3)
Supplier: Bioss
Description: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5517R-HRP

Anti-NFKBIE Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-5517R-HRP)
Supplier: Bioss
Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
UOM: 1 * 100 µl
Product Image-HEWL5188-6495

Convenience kits for inlet systems, QuickPick

Supplier: Agilent
Description: Split trap vent replacement kit (2 filters and 4 O-rings)

Product Image-SART6980121

Accessories for vacuum filtration units

Supplier: Sartorius
Description: Glass frit

Product Image-705-0845

Accessories for VELP BOD measurement system

Catalog Number: (705-0845)
Supplier: VELP SCIENTIFIC
Description: Potassium hydroxide trap for BOD sensor
UOM: 1 * 1 items
Product Image-516-8921

Vacuum membrane filter holder

Supplier: Cytiva (Formerly Pall Lab)
Description: Borosilicate glass, aluminium clamp.

Product Image-HEWL5060-9084

Traps for gas chromatographs

Supplier: Agilent
Description: Activated hydrocarbon trap packed with activated charcoal, should be used mainly for removing the trace amounts of hydrocarbons and organics from
carrier gases. Water and other contaminants, which cannot be trapped by the activated charcoal, may be removed by a Molecular Sieve 5A trap.

Product Image-LBCP5441400

Accessories for glove boxes, Protector®

Catalog Number: (LBCP5441400)
Supplier: LABCONCO
Description: Kit with HEPA filter and hose barb canister Ø 13 mm, for placing between the glove box and vacuum pump to protect the pump from particulate contaminants
UOM: 1 * 1 items
Product Image-MFLX96143-12

Black Rubber Vacuum Transfer Pump Tubing

Supplier: Avantor Fluid Handling
Description: Ideal for vacuum and pressure applications.

Product Image-ANTIA73804-96

Rabbit TRAP/CD40L ELISA Kit

Catalog Number: (ANTIA73804-96)
Supplier: ANTIBODIES.COM
Description: Rabbit TRAP/CD40L ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of rabbit TRAP/CD40L in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Product Image-MILFXX6602501

Flask and Neoprene Stopper

Catalog Number: (MILFXX6602501)
Supplier: Merck
Description: Simultaneously vacuum filter 12 samples for rapid analysis of retentate or filtrate. Numbered positions on the filter plate assure accurate sample tracking. Sealing stoppers maintain vacuum on unused sample cups. Accessory extension barrels increase sample volumes from 15 to 50 ml.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-5517R

Anti-IKB epsilon Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5517R)
Supplier: Bioss
Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5517R-A488

Anti-NFKBIE Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5517R-A488)
Supplier: Bioss
Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5517R-A750

Anti-IKB epsilon Ser157 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-5517R-A750)
Supplier: Bioss
Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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