Bicine, white powder

Supplier: MP Biomedicals

Synonyms: 2-(Bis(2-hydroxyethyl)amino)acetic acid, N,N-Bis(2-hydroxyethyl)glycine

0210100580 0210100525 0210100583 0210100591
ICNA0210100580EA 111 GBP
ICNA0210100580 ICNA0210100525 ICNA0210100583 ICNA0210100591
Bicine, white powder
Bicine

Bicine is an organic compound used as a buffering agent. It is a zwitterionic buffer and one of the Good's buffers . It is prepared by the reaction ofglycine with ethylene oxide, followed by hydrolysis of the resultant lactone. It is a recommended buffer for low temperature biochemical work. Used for the preparation of stable substrate solution for serum guanase determination.


Bicine is used in a thin layer ion exchange chromatography method for protein resolution.It is used in peptide and protein crystallization.Bicine is used in a kinetic study of a quaternary transition-state analogue complex of creatine kinase and in multiphasic buffer system for SDS-PAGE of proteins.


Soluble in water (10 mg/ml - clear, colourless solution; a saturated solution in water is 1,1 M )

Formula: C₆H₁₃NO₄
MW: 163,17 g/mol
Melting Pt: 190 °C (lit.)
Storage Temperature: Ambient
MDL Number: MFCD00004295
CAS Number: 150-25-4
EINECS: 205-755-1

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Specification Test Results

Identity Test Passes
FTIR Conforms to Reference
pH (1% aq soln) 4,0 - 6,0
OD260 nm (10% aq soln) <0,100
OD280 nm (10% aq soln) <0,100

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