α-Hydroxy-o-tolyl-β-D-glucopyranoside, powder

Supplier: MP Biomedicals

Synonyms: 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside, Salicoside, D(-)-Salicin, (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol, (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol, D(−)-Salicin

0210283305 0210283380 0210283310 0210283325
ICNA0210283305EA 60.7 GBP
ICNA0210283305 ICNA0210283380 ICNA0210283310 ICNA0210283325
α-Hydroxy-o-tolyl-β-D-glucopyranoside, powder
α-Hydroxy-o-tolyl β-D-glucopyranoside

Salicin is an alcoholic β-glucoside derived from willow bark that produces anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin Salicin is a substrate for β-glucosidase.


Salicin is used as an analgesic and antipyretic. It is also used as a substrate for beta-glucosidase and an inhibitor of Cox. It finds application as an anti-inflammatory agent. It is involved in antipyretic action without causing gastric injury.


Biochem/physiol Actions: It acts as a non-selective COX inhibitor, exhibiting IC50 values > 100 µM for COX-1 and COX-2.


Freely soluble in water (50 mg/ml-clear,colorless solution); soluble in alkalies, pyridine, glacial acetic acid; practically insoluble in ether and chloroform.

Formula: C₁₃H₁₈O₇
MW: 286,28 g/mol
Melting Pt: 199 - 201 °C
Density: 1,42 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00006590
CAS Number: 138-52-3
EINECS: 205-331-6
Merck Index: 12,08476

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Specification Test Results

Identity Test Passes
FTIR Conforms to Standard
194 - 204 °C Melting Point
Optical Rotation −65° ± 5° (c=3, water)

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