EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride) crosslinker

Supplier: G Biosciences
Danger

Synonyms: N'-(Ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine monohydrochloride, N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide monohydrochloride, 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDC hydrochloride, EDC, EDAC HCl, EDAC hydrochloride, 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, WSC HCl, EDC HCl

BC25-1 BC25-5
BC25-1EA 57.1 GBP
BC25-1 BC25-5
EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride) crosslinker
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride

EDC is a heterobifunctional, water-soluble, zero-length carbodiimide crosslinker that is used to couple carboxyl groups to primary amines. EDC activates carboxyl groups first and forms amine reactive O-acylisourea imtermediate that spontaneously reacts with primary amines to form an amide bond and isourea by-product.


The unstable nature of the intermediate in aqueous solutions makes 2-step coupling, however in conjunction with N-hydroxysuccinimide, a 2-step coupling is possible.
EDC is ideal for peptide immobilization and hapten-carrier protein conjugation

Formula: C₈H₁₇N₃·HCl
MW: 191,7 g/mol
Melting Pt: ∼ 113 °C
Storage Temperature: Refrigerator
MDL Number: MFCD00012503
CAS Number: 25952-53-8
EINECS: 247-361-2
UN: 2811
ADR: 6.1,III
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