Resiquimod (synthetic) ≥98% (by HPLC), white to off-white solid endotoxin-free
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 4-Amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, R-848
Ligand for TLR7 and TLR8.
R-848 is a selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Potent antitumor and antiviral compound. Stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 upregulation.
Soluble in DMSO, dichloromethane, 100% or 5% methanol; poorly soluble in acetonitrile or ethyl acetate.
Formula:
C₁₇H₂₂N₄O₂ MW: 314,389 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00937759 CAS Number: 144875-48-9 |
Specification Test Results
Purity | ≥98% (HPLC) |
Identity | Determined by MS, ¹H-NMR and ¹³C-NMR |
Source | Synthetic |
Endotoxin Content | Endotoxin-free |
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