YC-1 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol, Lificiguat

ALX420025M001 ALX420025M005
ENZOALX420025M001EA 45.1 GBP
ENZOALX420025M001 ENZOALX420025M005
YC-1 ≥98% (by HPLC)
YC-1

Guanylyl cyclase activator


Nitric oxide (NO) independent, superoxide-sensitive stimulator of soluble guanylyl cyclase (sGC), EC50=18.6μM. Induces concentration-dependent increase in cGMP levels in cultured cells and in rabbit aortic rings. Inhibits platelet adhesion to collagen. Non-specific phosphodiesterase inhibitor. YC-1 inhibits HIF-alpha activity in tumors resulting in blocked angiogenesis and an inhibition of tumor growth. Inhibits Na+ channel.Binds to [3H]BW202W92.

Formula: C₁₉H₁₆N₂O₂
MW: 304,349 g/mol
MDL Number: MFCD06407798
CAS Number: 170632-47-0

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