RO-3306 ≥95% (by 1H-NMR)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: (Z)-5-(Quinolin-6-ylmethylene)-2-((thiophen-2-ylmethyl)amino)thiazol-4(5H)-one, (Z)-5-(Quinolin-6-ylmethylene)-2-[(thiophen-2-ylmethyl)amino]thiazol-4(5H)-one

ALX270463M001 ALX270463M005
ENZOALX270463M001EA 74.1 GBP
ENZOALX270463M001 ENZOALX270463M005
RO-3306 ≥95% (by 1H-NMR)
RO-3306

CDK/cyclin inhibitor


Inhibitor of CDK1/cyclin B1 and CDK1/cyclin A. Reversibly arrests human cells at the G2/M border of the cell cycle. Allows for effective cell synchronisation in early mitosis. Downregulates expression of the antiapoptotic proteins Bcl-2 and survivin and blocks p53-mediated induction of p21 and MDM2.

Formula: C₁₈H₁₃N₃OS₂
MW: 351,5 g/mol
MDL Number: MFCD17392573
CAS Number: 872573-93-8

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