Thiolutin (from Streptomyces luteosporeus) ≥95% (by HPLC, TLC)

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 6-(Acetamido)-4-methyl-1,2-dithiolo[4,3-b]-pyrrol-5(4H)-one

BMLCT1070001 BMLCT1070005
ENZOBMLCT1070001EA 123 GBP
ENZOBMLCT1070001 ENZOBMLCT1070005
Thiolutin (from Streptomyces luteosporeus) ≥95% (by HPLC, TLC)
Thiolutin

Sulfur containing antibiotic. Potent inhibitor of bacterial and yeast RNA polymerases. Inhibits mRNA chain elongation. Inhibits adhesion of endothelial cells (HUVECs) to vitronectin (IC50=0.83 µM) thereby inhibiting tumor cell-induced angiogenesis in vivo. Inhibits transcription in C. albicans. Inhibits microbiological growth in beer. Active against soil borne pathogens.


  • RNA polymerase inhibitor


Yellow crystalline solid.


Soluble in DMSO (5mg/ml), very slightly soluble in water

Formula: C₈H₈N₂O₂S₂
MW: 228,3 g/mol
Storage Temperature: Freezer
CAS Number: 87-11-6
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