Etoposide ≥97%
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
(5R,5aR,8aR,9S)-9-(((4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one, 4'-Demethylepipodophyllotoxin 9-(4,6-O-Ethylidene-beta-D-glucopyranoside)
Topoisomerase inhibitor. p53 activator.
Antitumor reagent. Topoisomerase II inhibitor. Induces apoptosis by FasL. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cancer cells.
Semisynthetic derivative of podophyllotoxin.
Formula:
C₂₉H₃₂O₁₃ MW: 588,56 g/mol |
MDL Number:
MFCD00869325 CAS Number: 33419-42-0 |
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