Halt™ Phosphatase Inhibitor Cocktail
Supplier: Thermo Fisher Scientific
Phosphorylation and dephosphorylation is a molecular on/off switch that regulates a number of key biological pathways within the cell, including signal transduction, cell division, and apoptosis. The Halt Phosphatase Inhibitor Cocktail preserves phosphorylation of proteins in cell lysates and tissue extracts.
- All in one format - Halt Phosphatase Inhibitor Cocktail inhibits both serine/threonine as well as protein tyrosine phosphatases
- Compatible with standard protein assays
- User friendly storage at 2 to 8 °C - Halt Phosphatase Inhibitor Cocktail does not require frozen storage
- Convenient size - 1 ml of cocktail protects up to 100 ml of sample
The cocktail contains a mixture of four phosphatase inhibitors of broad specificity, including sodium fluoride, sodium orthovanadate, sodium pyrophosphate and -glycerophosphate. Unlike other commercially available phosphatase inhibitor cocktails, which protect against either serine/threonine phosphatases or protein tyrosine phosphatases, the Halt Phosphatase Inhibitor Cocktail protects phosphoproteins from both families of phosphatases. Conveniently packaged in a 100X format, the cocktail is stable at 4 °C and is compatible with common protein assays, including Bradford-based assays.
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