Tetrabromophenol blue, Sigma-Aldrich®

Supplier: SIGMA-ALDRICH MICROSCOPY

Synonyms: 4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide, 4,4'-(4,5,6,7-Tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromophenol] S,S-dioxide

M-Clarity™ quality level = MQ200

199311-1G 199311-5G
199311-1GEA 42.2 GBP
199311-1G 199311-5G
Tetrabromophenol blue, Sigma-Aldrich®
Tetrabromophenol blue

Tetrabromophenol Blue (TBPB) belongs to the group of sulfonephthalein acid-base indicators. It is employed in the potentiometric titration of the halogens with Hg₂(NO₃)₂. In addition, it has been used as a dye indicator in urine dipstick test to detect proteinuria. In this assay, with increasing concentration of urinary protein, TBPB sequentially changes colour from pale green to blue. Binding of TBPB to proteins is dependent on pH.


It is also used a diagnostic assay manufacturing, hematology, histology.

Formula: C₁₉H₆Br₈O₅S
MW: 985,55 g/mol
Melting Pt: 204 °C
Storage Temperature: Room Temperature
MDL Number: MFCD00005876
CAS Number: 4430-25-5
EINECS: 224-622-9
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Specification Test Results

Appearance (Form) Powder or Chunks
Infrared spectrum Conforms to Structure
Wavelength 606 - 616 nm
Extinction coefficient ≥55000
Purity (HPLC) ≥75.0 %
Visual Interval pH 3.0 Green Pass
Visual Interval pH 4.6 Royal Blue Pass

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