Human recombinant TGF-alpha (from E. coli)
Supplier: Shenandoah Biotechnology
Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein, containing 50 amino acids
- Functions as a mitogen to activate epithelial cell proliferation, growth and differentiation
TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier's disease.
It is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
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