Human recombinant TGF-alpha (from E. coli)

Supplier: Shenandoah Biotechnology

100-209AF-25UG 100-209AF-100U 100-209AF-250U 100-209AF-500U 100-209AF-1MG
SHBT100-209AF-25UGEA 71.6 GBP
SHBT100-209AF-25UG SHBT100-209AF-100U SHBT100-209AF-250U SHBT100-209AF-500U SHBT100-209AF-1MG
Human recombinant TGF-alpha (from E. coli)
Proteins and Peptides

Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family.


  • Animal-free
  • Produced from genetically modified E. coli
  • Monomeric protein, containing 50 amino acids
  • Functions as a mitogen to activate epithelial cell proliferation, growth and differentiation


TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier's disease.


It is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.


Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.


Caution: This product is for research use only and is not for use in humans.

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