Aloe emodin ≥95%, crystalline solid
Supplier: Cayman Chemical
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Warning
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Synonyms:
1,8-Dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione, 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone
Aloe-emodin is a hydroxyanthraquinone found in aloe vera leaves that has potent laxative action by inducing chloride secretion in colonic mucosa and releasing acetylcholine, which stimulates contraction of intestinal smooth muscle.
It also demonstrates anti-tumor activity (ED₅₀s=1 to 13 µM), inducing apoptosis in various cancer cells by increasing the production of reactive oxygen species. Aloe-emodin is reported to have estrogenic activity as a phytoestrogen and has been shown to inhibit breast cancer cell proliferation by downregulating ERα protein levels, and thus, suppressing transcriptional activation of the receptor.
Formula:
C₁₅H₁₀O₅ MW: 270,24 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00017373 CAS Number: 481-72-1 |
Specification Test Results
Purity | ≥95% |
Formulation | A Crystalline Solid |
λmax | 225, 255, 285, 430 nm |
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