Tris(hydroxypropyl)phosphine solution 0.5 M, Millipore®

Supplier: Merck Millipore (Novagen)

Synonyms: THPP, THP, Tris(3-hydroxypropyl)phosphine

71194-3 71194-4
71194-3EA 81.9 GBP
71194-3 71194-4
Tris(hydroxypropyl)phosphine solution 0.5 M, Millipore®
Tris(hydroxypropyl)phosphine

THP [Tris(hydroxypropyl)phosphine; C9H21O3P] is a water-soluble, odorless, sulfhydryl reducing agent that is more stable and effective than dithiothreitol (DTT).


Against oxidised glutathione, the reducing capacity of THP (0,232 meq/g) is greater than that of TCEP (0,182 meq/g). THP is also more resistant to air oxidation than DTT and is compatible with immobilized metal affinity chromatography with His•Bind® and Ni-NTA His•Bind resins at concentrations up to 1,0 mM. The common working concentration of THP for many applications is 1–5 mM. THP is provided as a ready-to-use 0,5 M solution in water.

Formula: C₉H₂₁O₃P
MW: 208,24 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00269835
CAS Number: 4706-17-6
UN: 2922
ADR: 8 (6.1),II

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Specification Test Results

Purity >80%

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