Nα-(p-Toluenesulphonyl)-DL-lysine chloromethyl ketone hydrochloride ≥95% (by elemental analysis), off-white solid, Calbiochem®

Supplier: Merck Millipore Calbiochem

Synonyms: Nα-p-Tosyl-DL-lysine chloromethyl ketone hydrochloride, TLCK

616382-250 616382-50
616382-250EA 480 GBP
616382-250 616382-50
Nα-(p-Toluenesulphonyl)-DL-lysine chloromethyl ketone hydrochloride ≥95% (by elemental analysis), off-white solid, Calbiochem®
Nalpha-(p-Toluenesulphonyl)-DL-lysine chloromethyl ketone hydrochloride

Inhibits trypsin-like serine proteinases.


Irreversibly inactivates trypsin without affecting chymotrypsin. Prevents nitric oxide production by activated macrophages by interfering with transcription of the iNOS gene. Blocks cell-cell adhesion and binding of HIV-1 virus to the target cells. In macrophages, blocks nitric oxide synthase induced by interferon-γ and lipopolysaccharides (EC₅₀=80 µM). Prevents endonucleolysis accompanying apoptotic death of HL-60 leukemia cells and normal thymocytes.

Formula: C₁₄H₂₂Cl₂N₂O₃S
MW: 369,31 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00012513
CAS Number: 4238-41-9

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Specification Test Results

Purity (Elemental Analysis) ≥95%

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